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Last Updated: December 22, 2024

Claims for Patent: 10,292,389


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Summary for Patent: 10,292,389
Title:Pediculicidal composition
Abstract: The disclosure provides a pediculicidal composition comprising a metal chelating agent; a carrier vehicle comprising water and an activating solvent system comprising an alcohol and a hydrocarbon. The carrier vehicle may be in the form of a solution, a cream, an ointment, a foam, a spray, an emulsion or a gel. The disclosure also provides method for use of a pediculicidal composition to treat human head lice and their eggs and methods for controlling head lice infestation.
Inventor(s): Harding; Ronald (Warrandyte, AU), Schulz; Lewis David (Fitzroy North, AU), Bowles; Vernon Morrison (Glen Iris, AU)
Assignee: DR. REDDY'S LABORATORIES, S.A. (Basel, CH)
Application Number:14/573,079
Patent Claims: 1. A composition comprising: 5,5'-dimethyl-2,2'-dipyridyl is present in an amount from 0.5% to 1% by weight; benzyl alcohol is present in an amount from 1% to 3% by weight; mineral oil is present in an amount from 20% to 30% by weight; water is present in an amount from 60% to 90% by weight; carbomer is present in an amount from 0.1% to 0.5% by weight; trolamine is present in an amount from 0.1% to 1% by weight; butylated hydroxy toluene is present in an amount from 0.2% to 1% by weight; and polysorbate 20 is present in an amount from 0.5 to 1% by weight.

2. The composition of claim 1, wherein said composition is a lotion, cream or gel composition comprising 0.74% by weight 5,5'-dimethyl-2,2'-dipyridyl.

3. The composition of claim 1, wherein said composition is a lotion or gel composition comprising 24% by weight mineral oil.

4. The composition of claim 1, wherein said composition is a lotion or gel composition comprising 2% by weight benzyl alcohol.

5. The composition of claim 1, comprising 2% by weight benzyl alcohol, 24% mineral oil, 1% polysorbate 20 and 0.74%, 5,5'-dimethyl-2,2'-dipyridyl and said composition exhibits a greater lousicidal activity than a composition that comprises benzyl alcohol, mineral oil, and polysorbate 20 in the same weight percent, but that does not comprise 5,5'-dimethyl-2,2'-dipyridyl.

6. The composition of claim 1, comprising 2% by weight benzyl alcohol, 24% mineral oil, 1% polysorbate 20 and 0.74%, 5,5'-dimethyl-2,2'-dipyridyl and said composition exhibits a greater ovicidal and lousicidal activity than a composition that comprises benzyl alcohol, mineral oil, and polysorbate 20 in the same weight percent, but that does not comprise 5,5'-dimethyl-2,2'-dipyridyl.

7. An aqueous composition for topical application to a subject comprising by weight: 0.74% 5,5'-dimethyl-2,2'-dipyridyl; 24% mineral oil; 0.15% Carbomer; 0.20% Trolamine; 2.00% benzyl alcohol, 1% polysorbate 20, 0.5% butylated hydroxytoluene and balance purified water.

8. A method of treating a lice infestation, the method comprising topically applying to a host having a lice infestation an effective amount of a composition according to claim 1.

9. The method of claim 8, wherein topical application of said composition kills lice and inhibits egg hatching.

10. The method of claim 8, wherein topical application of said composition to said host kills more lice than a vehicle composition comprising the same components except for 5,5'-dimethyl 2,2'-dipyridyl.

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