Claims for Patent: 10,392,406

Summary for Patent: 10,392,406

Title:	Substituted polycyclic pyridone derivatives and prodrugs thereof
Abstract:	The present invention provides the following compounds having anti-viral activity. ##STR00001## A.sup.1 is CR.sup.1AR.sup.1B, S or O; A.sup.2 is CR.sup.2AR.sup.2B, S or O; A.sup.3 is CR.sup.3AR.sup.3B, S or O; A.sup.4 is CR.sup.4AR.sup.4B, S or O; the number of hetero atoms among atoms constituting the ring which consists of A.sup.1, A.sup.2, A.sup.3, A.sup.4, nitrogen atom adjacent to A.sup.1 and carbon atom adjacent to A.sup.1, is 1 or 2; R.sup.1A and R.sup.1B are each independently hydrogen, halogen, alkyl, or the like; R.sup.2A and R.sup.2B are each independently hydrogen, halogen, alkyl, or the like; R.sup.3A and R.sup.3B are each independently hydrogen, halogen, alkyl, or the like; R.sup.4A and R.sup.4B are each independently hydrogen, halogen, alkyl, or the like; R.sup.3A and R.sup.3B may be taken together to form non-aromatic carbocycle or non-aromatic heterocycle; X is CH.sub.2, S or O; R.sup.1 is each independently halogen, hydroxy, or the like; m is any integer of 0 to 2; and n is any integer of 1 to 2.
Inventor(s):	Kawai; Makoto (Osaka, JP)
Assignee:	SHIONOGI & CO., LTD. (Osaka, JP)
Application Number:	15/569,191
Patent Claims:	1. A compound represented by the following formula: ##STR00251## or its pharmaceutically acceptable salt.