Claims for Patent: 10,420,760

Summary for Patent: 10,420,760

Title:	Pharmaceutical compositions and methods of using the same
Abstract:	Novel pharmaceutical compositions including cocaine hydrochloride and methods of treating patients using those pharmaceutical compositions are described.
Inventor(s):	Moshal; Jeffrey M. (Allentown, PA), Libman; Michael (Allentown, PA)
Assignee:	GENUS LIFESCIENCES INC. (Allentown, PA)
Application Number:	15/935,776
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 10,420,760
Patent Claims:	1. A method for induction of local anesthesia prior to performing a diagnostic procedure on, through, or adjacent to a mucous membrane of the nasal cavities of a patient comprising: determining an estimated glomerular filtration rate for a patient; soaking a plurality of absorbent articles in an aqueous solution comprising sodium benzoate, citric acid, and about 4% cocaine hydrochloride, by weight; and contacting at least one of the plurality of absorbent articles with a mucous membrane of the patient for up to about 20 minutes to reduce sensation in a body region of the patient if the estimated glomerular filtration rate ranges from about 15 mL/min./1.73 m.sup.2 to less than about 60 mL/min./1.73 m.sup.2. 2. The method of claim 1, wherein the estimated glomerular filtration rate ranges from about 44 mL/min./1.73 m.sup.2 to less than about 60 mL/min./1.73 m.sup.2. 3. The method of claim 1, wherein the method is not performed more than once in a 24-hour period. 4. The method of claim 1, wherein the aqueous solution further comprises at least one coloring additive. 5. The method of claim 2, wherein the aqueous solution further comprises at least one coloring additive. 6. The method of claim 3, wherein the aqueous solution further comprises at least one coloring additive. 7. The method of claim 1, wherein the diagnostic procedure comprises nasal endoscopy. 8. The method of claim 1, wherein the diagnostic procedure comprises laryngoscopy. 9. The method of claim 1, wherein the diagnostic procedure comprises nasopharyngeal laryngoscopy. 10. The method of claim 1, wherein the diagnostic procedure comprises transnasal esophagoscopy. 11. The method of claim 1, wherein the diagnostic procedure comprises nasal stroboscopy. 12. A method for induction of local anesthesia prior to performing a medical procedure on, through, or adjacent to a mucous membrane of the nasal cavities of a patient comprising: determining an estimated glomerular filtration rate for a patient; soaking a plurality of absorbent articles in an aqueous solution comprising sodium benzoate, citric acid, and about 4% cocaine hydrochloride, by weight; and contacting at least one of the plurality of absorbent articles with a mucous membrane of the patient for up to about 20 minutes to reduce sensation in a body region of the patient if the estimated glomerular filtration rate ranges from about 15 mL/min./1.73 m.sup.2 to less than about 60 mL/min./1.73 m.sup.2. 13. The method of claim 12, wherein the estimated glomerular filtration rate ranges from about 44 mL/min./1.73 m.sup.2 to less than about 60 mL/min./1.73 m.sup.2. 14. The method of claim 12, wherein the method is not performed more than once in a 24-hour period. 15. The method of claim 12, wherein the aqueous solution further comprises at least one coloring additive. 16. The method of claim 13, wherein the aqueous solution further comprises at least one coloring additive. 17. The method of claim 14, wherein the aqueous solution further comprises at least one coloring additive. 18. The method of claim 12, wherein the medical procedure comprises nasal endoscopy. 19. The method of claim 12, wherein the medical procedure comprises laryngoscopy. 20. The method of claim 12, wherein the medical procedure is at least one procedure selected from the group consisting of nasopharyngeal laryngoscopy, nasal laryngoscopy, nasal debridement, intraturbinate methylprednisolone acetate injection, turbinate reduction, transnasal esophagoscopy, sinuplasty, nasal cauterization, stroboscopy, nasal stroboscopy, and polypectomy.