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Last Updated: April 3, 2025

Claims for Patent: 10,441,630

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Summary for Patent: 10,441,630

Title:	Topical formulations and uses thereof
Abstract:	Provided herein include formulations for topical administration, such as ophthalmic formulations, and methods of using such formulations. In some aspects and embodiments the formulations may include a polyoxyl lipid or fatty acid, and or a polyalkoxylated alcohol and may include nanomicelles. Also include methods of treating or preventing diseases or conditions, such as ocular diseases or conditions.
Inventor(s):	Ashim K. Mitra, Sidney L. Weiss, Eugene J. McNally
Assignee:	Sun Pharmaceutical Industries Ltd
Application Number:	US15/153,640
Patent Claims:	1. An aqueous clear nanomicellar ophthalmic formulation, comprising: an active agent, 0.5-4.5% by weight of a polymer comprising HCO-40, HCO-60, HCO-80, HCO-100, polyoxyl 35 castor oil or combinations thereof; and 0.02-0.08% of a polyalkoxylated alcohol. 2. The aqueous clear nanomicellar ophthalmic formulation of claim 1, wherein said polymer comprises HCO-40, HCO-60, HCO-80, HCO-100 or combinations thereof. 3. The aqueous clear nanomicellar ophthalmic formulation of claim 1, wherein said polyalkoxylated alcohol is Octoxynol-40. 4. The aqueous clear nanomicellar ophthalmic formulation of claim 2, wherein said polymer is HCO-40. 5. The aqueous clear nanomicellar ophthalmic formulation of claim 2, wherein said polymer is HCO-60. 6. The aqueous clear nanomicellar ophthalmic formulation of claim 1, wherein said polymer is 1-4% by weight. 7. The aqueous clear nanomicellar ophthalmic formulation of claim 3, wherein Octoxynol-40 is 0.05% by weight.

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