Claims for Patent: 10,463,598

Summary for Patent: 10,463,598

Title:	Compositions and kits for the removal of irritating compounds from bodily surfaces
Abstract:	The invention provides compositions, methods and kits for the removal of harmful or irritating substances from bodily surfaces. Kits may include a composition containing capsaicin and a capsaicin-cleansing composition, e.g., a composition in which capsaicin is soluble.
Inventor(s):	Angel; Arturo J. (Santa Rosa, CA), Litle; Larry W. (Lee's Summit, MO), Bley; Keith R. (Menlo Park, CA), Wilcox; Allan L. (Mountain View, CA), Jamieson; Gene C. (Boulder Creek, CA), Muhammad; Naweed (Fremont, CA)
Assignee:	Averitas Pharma Inc. (Morristown, NJ)
Application Number:	15/377,804
Patent Claims:	1. An aqueous composition for cleansing capsaicin from a bodily surface comprising: a) about 80 to about 99 percent w/w polyethylene glycol (PEG); and b) about 0.1 to about 4.0 percent w/w polyacrylate thickening agent, wherein the aqueous composition has a viscosity of between 100 to 8000 cps. 2. The aqueous composition of claim 1, comprising: about 84 to about 94 percent w/w polyethylene glycol (PEG). 3. The aqueous composition of claim 2, further comprising a stabilizer. 4. The aqueous composition of claim 3, further comprising a cooling agent. 5. The aqueous composition of claim 3, comprising: a) about 87 to about 91 percent w/w polyethylene glycol (PEG); b) about 0.3 to about 2 percent w/w polyacrylate thickening agent; c) about 0.01 to about 0.03 percent w/w butylated hydroxyanisole; d) about 0.02 to about 0.2 percent w/w edetate sodium; and e) the balance water; wherein the aqueous composition is at a pH of about 7.0 to about 7.7. 6. The aqueous composition of claim 5, comprising: a) about 89.08 percent w/w PEG 300; b) about 1.0 percent w/w polyacrylate thickening agent; c) about 0.02 percent w/w butylated hydroxyanisole; d) about 0.1 percent w/w disodium edetate; and e) the balance water; wherein the aqueous composition is at a pH of about 7.5. 7. The aqueous composition of claim 1, having a pH between about 7.0 and about 7.7. 8. The aqueous composition of claim 2, comprising about 90 percent w/w polyethylene glycol (PEG). 9. The aqueous composition of claim 8, further comprising: i) about 0.1 to about 2.0 percent w/w polyacrylate thickening agent; and ii) the balance water; wherein the aqueous composition is at a pH between about 7.0 and about 7.7. 10. The aqueous composition of claim 1, wherein the PEG is PEG 200 to PEG 600. 11. The aqueous composition of claim 1, in which capsaicin has a solubility of at least about 10 to 25 percent w/w. 12. The aqueous composition of claim 11, in which capsaicin has a solubility of about 10 percent w/w. 13. The aqueous composition of claim 11, in which capsaicin has a solubility of about 20 percent w/w. 14. The aqueous composition of claim 11, in which capsaicin has a solubility of about 25 percent w/w. 15. The aqueous composition of claim 1, which is a surfactant-free gel. 16. The aqueous composition of claim 1, wherein the viscosity is between 4000 cps to 8000 cps. 17. The aqueous composition of claim 16, wherein the viscosity is between 4000 to 5000 cps. 18. The aqueous composition of claim 1, wherein the viscosity is between 2000 to 5000 cps. 19. The aqueous composition of claim 1, wherein the viscosity is between 100 to 1000 cps. 20. The aqueous composition of claim 1, which is substantially free of particulates. 21. The aqueous composition of claim 1, wherein the polyacrylate thickening agent is an acrylic acid/ethylacrylate copolymer or a carboxyvinyl polymer.