Claims for Patent: 10,617,668

Summary for Patent: 10,617,668

Title:	Pharmaceutical formulations
Abstract:	The present invention relates to formulations including compounds of Formula (I), ##STR00001## or prodrug, or a pharmaceutically acceptable salt thereof.
Inventor(s):	Wang; Wenhua (Newtown, PA), Outwin; Todd (Chalfont, PA), Joseph; Thomas C. (Oakford, PA)
Assignee:	Janssen Pharmaceutica NV (Beerse, BE)
Application Number:	15/400,005
Patent Claims:	1. An orally administrable pharmaceutical tablet comprising (a) a compound which is 1-(.beta.-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethy- l]benzene), or a prodrug or pharmaceutically acceptable salt thereof present in an amount within a range of from about 1% to about 80% by weight; (b) a diluent or filler consisting of a combination of microcrystalline cellulose and lactose, wherein the diluent or filler is present in an amount within a range of from about 10% to about 95% by weight; (c) croscarmellose sodium in an amount within a range of from about 0.1 to about 20% by weight; (d) hydroxypropyl cellulose in an amount within a range of from about 0.1 to about 20% by weight; and (e) magnesium stearate in an amount within a range of from about 0.1% to about 5% by weight; wherein the % by weight is based on a weight of the tablet. 2. The pharmaceutical tablet of claim 1, wherein the compound of (a) is 1-(.beta.-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethy- l]benzene) hemihydrate. 3. The pharmaceutical tablet of claim 1, wherein the compound of (a) is present in an amount of about 25 mg to about 600 mg. 4. The pharmaceutical tablet of claim 1, wherein the compound of (a) is present in an amount of about 50 mg to about 300 mg. 5. The pharmaceutical tablet of claim 1, wherein the compound of (a) is present in an amount of about 100 mg. 6. The pharmaceutical tablet of claim 1, wherein the compound of (a) is present in an amount of about 300 mg. 7. A method for treating a sodium-dependent glucose transporter mediated disorder, said method comprising administering to a patient in need thereof, the pharmaceutical tablet of claim 1. 8. The method of claim 7 wherein the compound of (a) is administered at a dose of from about 50 mg to about 300 mg once daily. 9. The method of claim 7 wherein the compound of (a) is administered at a dose of about 100 mg per day. 10. The method of claim 7 wherein the compound of (a) is administered at a dose of about 300 mg per day.