You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: December 23, 2024

Claims for Patent: 10,626,088

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 10,626,088

Title:	Determining degradation of 3,4-diaminopyridine
Abstract:	The present invention relates to methods of determining the purity of a sample of 3,4-diaminopyridine comprising determining the presence, absence, or amount of a dimer of 3,4-diaminopyridine or a dimer of 3,4-diaminopyridine in the form of a salt, solvate or complex or a combination thereof. The invention also relates to methods of detecting and quantitating degradation in a sample of 3,4-diaminopyridine. Dimers of 3,4-diaminopyridine and methods of making and isolating the same are also provided.
Inventor(s):	Schiehser; Guy Alan (Washington Crossing, PA), Shah; Rajendra (Edison, NJ), Zhao; Wenyi (Monroe Township, NJ)
Assignee:	JACOBUS PHARMACEUTICAL COMPANY, INC. (Princeton, NJ)
Application Number:	15/695,043
Patent Claims:	1. A 3,4-Diaminopyridine dimer that is ##STR00004## or a tautomer thereof; in the form of a salt, solvate, or complex, or a combination thereof. 2. The 3,4-diaminopyridine dimer of claim 1, wherein the salt comprises a sulfate group. 3. The 3,4-diaminopyridine dimer of claim 1, wherein the complex comprises a monohydrate group. 4. The 3,4-diaminopyridine dimer of claim 1, wherein the solvate comprises a monomethanolate group. 5. The 3,4-diaminopyridine dimer of claim 1, wherein salt comprises a sulfate, the solvate comprises a monohydrate, and the complex comprises a monomethanolate. 6. The 3,4-diaminopyridine dimer of claim 1, wherein the 3,4-diaminopyridine dimer is 3,4-diaminopyridine dimer sulfate monohydrate monomethanolate. 7. The dimer of claim 6 in amorphous solid form.

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.