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Last Updated: December 28, 2024

Claims for Patent: 10,857,161

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Summary for Patent: 10,857,161

Title:	Non-hormonal steroid modulators of NF-kB for treatment of disease
Abstract:	Provided herein is a pharmaceutical composition comprising a compound having the structural formula
Inventor(s):	McCall John M., Hoffman Eric, Nagaraju Kanneboyina
Assignee:	ReveraGen BioPharma, Inc.
Application Number:	US16226061
Patent Claims:	2. The pharmaceutical composition of claim 1 , wherein the therapeutically effective amount is between 10 mg to 200 mg of the compound.3. The pharmaceutical composition of claim 1 , wherein the composition is formulated as a tablet or capsule.4. The pharmaceutical composition of claim 1 , wherein the suspension further comprises a flavoring agent.5. The pharmaceutical composition of claim 1 , wherein the compound is present in an amount effective to treat or reduce the symptoms of muscular dystrophy.6. The pharmaceutical composition of claim 5 , wherein the muscular dystrophy is chosen from Duchenne muscular dystrophy claim 5 , Becker muscular dystrophy claim 5 , limb girdle muscular dystrophy claim 5 , congenital muscular dystrophy claim 5 , facioscapulohumeral muscular dystrophy claim 5 , myotonic muscular dystrophy claim 5 , oculopharyngeal muscular dystrophy claim 5 , distal muscular dystrophy claim 5 , and Emery-Dreifuss muscular dystrophy.7. The pharmaceutical composition of claim 6 , wherein the muscular dystrophy is Duchenne muscular dystrophy.8. The pharmaceutical composition of claim 6 , wherein the muscular dystrophy is Becker muscular dystrophy.9. The pharmaceutical composition of claim 6 , wherein the muscular dystrophy is limb girdle muscular dystrophy.10. The pharmaceutical composition of claim 6 , wherein the muscular dystrophy is congenital muscular dystrophy.11. The pharmaceutical composition of claim 6 , wherein the muscular dystrophy is facioscapulohumeral muscular dystrophy.12. The pharmaceutical composition of claim 6 , wherein the muscular dystrophy is myotonic muscular dystrophy.13. The pharmaceutical composition of claim 6 , wherein the muscular dystrophy is oculopharyngeal muscular dystrophy.14. The pharmaceutical composition of claim 6 , wherein the muscular dystrophy is distal muscular dystrophy.15. The pharmaceutical composition of claim 6 , wherein the muscular dystrophy is Emery-Dreifuss muscular dystrophy.17. The method of claim 16 , wherein the compound is administered orally.18. The method of claim 17 , wherein the compound is administered as a solution or suspension.19. The method of claim 18 , wherein the solution or suspension further comprises a flavoring agent.20. The method of claim 16 , wherein the muscular dystrophy is chosen from Duchenne muscular dystrophy claim 16 , Becker muscular dystrophy claim 16 , limb girdle muscular dystrophy claim 16 , congenital muscular dystrophy claim 16 , facioscapulohumeral muscular dystrophy claim 16 , myotonic muscular dystrophy claim 16 , oculopharyngeal muscular dystrophy claim 16 , distal muscular dystrophy claim 16 , and Emery-Dreifuss muscular dystrophy.

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