Claims for Patent: 10,881,798

Summary for Patent: 10,881,798

Title:	Needle assisted injection device having reduced trigger force
Abstract:	An injector includes a trigger mechanism including: a trigger member disposed about an axis having an aperture and a protrusion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a trigger engagement member configured to engage the aperture of the trigger member when the trigger member is in a pre-firing condition; an energy source associated with the ram for powering the ram to expel the medicament; and a user-operable firing-initiation member having an aperture engaged with the protrusion of the trigger member and operable for causing an axial translation of the trigger member in a proximal direction from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.
Inventor(s):	Travanty; Michael (Minneapolis, MN)
Assignee:	ANTARES PHARMA, INC. (Ewing, NJ)
Application Number:	15/783,407
Patent Claims:	1. An injector, comprising: a trigger mechanism including: a trigger member disposed about an axis, the trigger member having a trigger member protrusion and an opening defined by a trigger member opening wall, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a trigger engagement member configured to be positioned in the opening and engage the trigger member opening wall when the trigger member is in a pre-firing condition; an energy source associated with the ram for powering the ram to expel the medicament; and a guard including a guard aperture receiving the trigger member protrusion and operable for causing an axial translation of the trigger member in a proximal direction from the pre-firing condition to a firing condition in which the trigger engagement member is disengaged from the trigger member opening wall to avow the energy source to fire the ram. 2. The injector of claim 1, further comprising an injector housing, wherein the guard includes a skin-contacting member disposed at a distal end of the injector that is movable proximally with respect to the housing when a force is applied to the skin-contacting member at the distal end of the injector, the guard being associated with the trigger member and configured to cause the axial translation of the trigger member in a proximal direction from the pre-firing condition to the firing condition upon a proximal movement of the guard with respect to housing. 3. The injector of claim 2, wherein the guard is retractable and is configured to expose a needle connected to the medicament container upon the proximal movement of the guard. 4. The injector of claim 3, wherein the needle is in fluid communication with the medicament container for injecting the medicament expelled therefrom during firing. 5. The injector of claim 3, wherein the energy source and the needle are configured for jet injecting the medicament through the needle. 6. The injector of claim 3, wherein the energy source and the needle are configured for injecting the medicament at an average velocity of at least about 1,000 cm/sec within the needle. 7. The injector of claim 1, wherein the energy source is configured to pressurize the medicament to between about 90 p.s.i. and about 600 p.s.i. to jet inject the medicament. 8. The injector of claim 1, further comprising an end cap, said end cap comprising a ram holding member that axially retains the ram assembly in a proximal position against action of the energy source in the pre-firing condition. 9. The injector of claim 8, wherein the ram holding member engages the trigger engagement member to axially retain the ram assembly in a proximal position against action of the energy source in the pre-firing condition. 10. The injector of claim 9, further comprising, a latch retention angle defined by the axis and a contact surface of the ram holding member and the trigger engagement member. 11. The injector of claim 10, wherein the latch retention angle is between about 35.degree. and about 45.degree.. 12. The injector of claim 10, wherein the latch retention angle is between about 75.degree. and about 85.degree.. 13. The injector of claim 9, wherein in the firing condition, the ram assembly is disengaged from the trigger member opening wall, and the energy source overcomes the engagement between the trigger engagement member and the ram holding member. 14. The injector of claim 9, wherein the ram holding member includes a projection that includes a bulge and a groove that are engaged with the trigger engagement member, and the trigger member opening wall retains the engagement of the trigger engagement member with the bulge and groove in the pre-firing condition. 15. The injector of claim 1, further comprising a container support that is configured for holding the medicament container during injection, and wherein the ram assembly is configured to engage the container support to lock-out the injector after an injection. 16. The injector of claim 15, wherein proximal movement of the guard is blocked by the ram assembly when the injector is locked-out. 17. The injector of claim 1, wherein a pre-firing color gamut is visible from an exterior of the injector in the pre-firing condition, the injector further comprising: a housing including a window; and an indicator having an indicator color that is absent from the pre-firing color gamut, which color is hidden from view within the housing in the pre-firing condition, wherein in a fired condition, the indicator color is visible through the window from an exterior of the injector for indicating the fired condition. 18. The injector of claim 17, wherein the ram assembly includes the indicator. 19. The injector of claim 18, wherein the ram assembly entirely occludes the window in the fired condition. 20. The injector of claim 1, wherein the medicament comprises an androgen.