You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: December 22, 2024

Claims for Patent: 10,961,250

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 10,961,250

Title:	Short-acting benzodiazepine salts and their polymorphic forms
Abstract:	The invention relates to besylate salts of the compound of formula (I): ##STR00001## Methods of preparing the salts, and their use as medicaments, in particular for sedative or hypnotic, anxiolytic, muscle relaxant, or anticonvulsant purposes is also described.
Inventor(s):	Tilbrook; Gary Stuart (Huntingdon, GB), Quegan; Louisa Jane (Cambridge, GB)
Assignee:	PAION UK LIMITED (Cambridge, GB)
Application Number:	16/598,876
Patent Claims:	1. A pharmaceutical composition comprising a besylate salt of the compound of formula (I) ##STR00005## and at least one pharmaceutically acceptable carrier, excipient or diluent, wherein the pharmaceutical composition is an aqueous solution comprising dextrose or saline. 2. The pharmaceutical composition according to claim 1, wherein the aqueous solution comprises saline. 3. The pharmaceutical composition according to claim 1, wherein the aqueous solution comprises dextrose. 4. A lyophilized composition comprising a besylate salt of the compound of formula (I) ##STR00006## and at least one pharmaceutically acceptable carrier, excipient or diluent, and dextrose or saline. 5. An aqueous pharmaceutical composition comprising of the lyophilized composition of claim 4. 6. The aqueous pharmaceutical composition according to claim 5, wherein the aqueous solution comprises saline. 7. The aqueous pharmaceutical composition according to claim 5, wherein the aqueous solution comprises dextrose. 8. A method of producing sedation in a subject, comprising administering to the subject an effective amount of a pharmaceutical composition comprising a besylate salt of the compound of formula (I) ##STR00007## and at least one pharmaceutically acceptable carrier, excipient or diluent, wherein the pharmaceutical composition is an aqueous solution comprising dextrose or saline. 9. The method according to claim 8, wherein the aqueous solution comprises saline. 10. The method according to claim 8, wherein the aqueous solution comprises dextrose.

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.