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Last Updated: December 17, 2024

Claims for Patent: 10,987,347

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Summary for Patent: 10,987,347

Title:	Pharmaceutical compositions and methods of using the same
Abstract:	Novel pharmaceutical compositions including cocaine hydrochloride and methods of treating patients using those pharmaceutical compositions are described.
Inventor(s):	Moshal; Jeffrey M. (Allentown, PA), Libman; Michael (Allentown, PA)
Assignee:	GENUS LIFESCIENCES INC. (Allentown, PA)
Application Number:	16/517,926
Patent Claims:	1. A method for induction of local anesthesia prior to performing a medical procedure on, through, or adjacent to a mucous membrane of a nasal cavity of a patient comprising: determining a Child-Pugh score for a patient; soaking a plurality of absorbent articles in an aqueous solution comprising, by weight, about 3.6% to about 4.4% cocaine hydrochloride, about 0.07% to about 0.20% sodium benzoate, and citric acid; and contacting at least one of the plurality of absorbent articles with a mucous membrane of the patient for up to about 20 minutes to reduce sensation in a body region of the patient, if the patient has a Grade A Child-Pugh score. 2. The method of claim 1, wherein the aqueous solution further comprises at least one coloring additive. 3. A method for induction of local anesthesia prior to performing a medical procedure on, through, or adjacent to a mucous membrane of a nasal cavity of a patient comprising: determining a Child-Pugh score for a patient; soaking a plurality of absorbent articles in an aqueous solution comprising, by weight, about 3.6% to about 4.4% cocaine hydrochloride, about 0.07% to about 0.20% sodium benzoate, and citric acid; and contacting at least one of the plurality of absorbent articles with a mucous membrane of the patient for up to about 20 minutes to reduce sensation in a body region of the patient, if the patient has a Grade A or Grade B Child-Pugh score. 4. The method of claim 3, wherein the aqueous solution further comprises at least one coloring additive. 5. The method of claim 1, wherein the aqueous solution comprises about 0.125% citric acid. 6. The method of claim 3, wherein the aqueous solution comprises about 0.125% citric acid. 7. The method of claim 1, wherein a pH of the aqueous solution is 2 to 4. 8. The method of claim 3, wherein a pH of the aqueous solution is 2 to 4.

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