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Last Updated: December 22, 2024

Claims for Patent: 11,154,526


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Summary for Patent: 11,154,526
Title:Methods of treating mixed dyslipidemia
Abstract: The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Inventor(s): Osterloh; Ian (Kent, GB), Wicker; Pierre (Mystic, CT), Braeckman; Rene (Richboro, PA), Soni; Paresh (Mystic, CT), Manku; Mehar (Birmingham, GB)
Assignee: Amarin Pharmaceuticals Ireland Limited (Dublin, IE)
Application Number:17/027,069
Patent Claims: 1. A method of reducing triglyceride levels in a subject on anticoagulant/antiplatelet/thrombolytic therapy, having triglyceride levels of at least about 500 mg/dl, and having atrial fibrillation and/or atrial flutter, the method comprising administering to the subject about 4 g of ethyl icosapentate per day.

2. The method of claim 1, wherein the subject is on statin therapy.

3. The method of claim 1, wherein the subject has a baseline LDL-C level of about 40 mg/dL to about 100 mg/dL.

4. The method of claim 1, wherein the ethyl icosapentate is present in a pharmaceutical composition and the ethyl icosapentate comprises at least about 96 wt. % of all omega-3 fatty acids in the pharmaceutical composition.

5. The method of claim 4, wherein about 1 g of the pharmaceutical composition is present in each of 4 capsules.

6. The method of claim 1, wherein the subject is administered the ethyl icosapentate for a period of at least about 2 years.

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