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Last Updated: December 22, 2024

Claims for Patent: 11,236,121

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Summary for Patent: 11,236,121

Title:	Crystalline 19-nor C3,3-disubstituted C21-N-pyrazolyl steroid
Abstract:	This invention relates to a 19-nor C3,3-disubstituted C21-pyrazolyl steroid of Formula (I) and crystalline solid forms and compositions thereof. Also disclosed herein are methods of making crystalline solid forms of the 19-nor C3,3-disubstituted C21-pyrazolyl steroid of Formula (I) and methods of using the 19-nor C3,3-disubstituted C21-pyrazolyl steroid of Formula (I) or crystalline solid forms, pharmaceutically acceptable salts, and pharmaceutically acceptable compositions thereof.
Inventor(s):	Watson Paul Steven, Berner Bret, Reid John Gregory, Wang Jian, Doherty James J., Kanes Stephen Jay
Assignee:	Sage Therapeutics, Inc.
Application Number:	US16326977
Patent Claims:	2. The crystalline solid form of claim 1 , wherein the peak between and including 9.7 to 10.1 is 9.9 degrees in 2θ claim 1 , the peak between and including 11.6 to 12.0 is 11.8 degrees in 2θ claim 1 , the peak between and including 13.2 to 13.6 is 13.4 degrees in 2θ claim 1 , the peak between and including 14.2 to 14.6 is 14.4 degrees in 2θ claim 1 , the peak between and including 14.6 to 15.0 degrees is 14.8 in 20 claim 1 , the peak between and including 16.8 to 17.2 is 17.0 degrees in 2θ claim 1 , the peak between and including 20.5 to 20.9 is 20.7 degrees in 2θ claim 1 , the peak between and including 21.3 to 21.7 is 21.5 degrees in 2θ claim 1 , the peak between and including 21.4 to 21.8 is 21.6 degrees in 2θ claim 1 , and the peak between and including 22.4 to 22.8 is 22.6 degrees in 2θ.4. The crystalline solid form of claim 3 , wherein the peak between and including 9.7 to 10.1 is 9.9 degrees in 2θ claim 3 , the peak between and including 14.6 to 15.0 is 14.8 degrees in 2θ claim 3 , the peak between and including 16.8 to 17.2 is 17.0 degrees in 2θ claim 3 , the peak between and including 20.5 to 20.9 is 20.7 degrees in 2θ claim 3 , and the peak between and including 21.3 to 21.7 is 21.5 degrees in 2θ.

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