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Last Updated: April 5, 2025

Claims for Patent: 11,571,518

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Summary for Patent: 11,571,518

Title:	Emergency devices
Abstract:	Described herein are syringe devices comprising a syringe including a therapeutic dose of at least one drug to be used in a drug or substance overdose.
Inventor(s):	Mark J. Flather, Karen K. Daniels, Thomas Moll
Assignee:	Zmi Pharma Inc
Application Number:	US16/422,639
Patent Claims:	1. An emergency syringe device comprising: a syringe including a therapeutic dose of at least one opioid antagonist, and a stopper; and a plunger assembly including a plunger rod, an actuator including at least one guide rail, and a spacer, wherein the at least one guide rail travels against a front surface of the spacer, wherein the plunger assembly is configured to move the stopper a predetermined distance without a user touching the plunger rod or being able to retract the plunger rod. 2. The syringe device of claim 1, wherein the plunger assembly is configured to provide substantially identical doses of the at least one opioid antagonist even if more or less opioid antagonist is provided in the syringe by moving the stopper a predetermined distance. 3. The syringe device of claim 1, further including: an encasement configured to house the syringe. 4. The syringe device of claim 3, wherein the encasement includes a window configured to allow the user to view the at least one opioid antagonist in the syringe. 5. The syringe device of claim 3, wherein the encasement includes a needle guard configured to allow the user to cover a needle associated with the syringe after use. 6. The syringe device of claim 1, wherein the at least one opioid antagonist is naloxone, a salt thereof, a derivative thereof, or a prodrug thereof. 7. The syringe device of claim 1, wherein the at least one opioid antagonist is naloxone. 8. The syringe device of claim 6, wherein the syringe device is configured to deliver about 5 mg of naloxone or a salt thereof. 9. The syringe device of claim 6, wherein the syringe device is configured to deliver about 15 mg of naloxone or a salt thereof. 10. The syringe device of claim 1, wherein the actuator and the spacer are configured to be secured around the plunger rod. 11. The syringe device of claim 1, wherein the actuator includes a finger depression location. 12. The syringe device of claim 1 configured for use in an opioid overdose. 13. A method for administering a therapeutic dose of at least one opioid antagonist, the method comprising: providing an emergency syringe device; advancing a stopper on the syringe device through a syringe including the therapeutic dose of the at least one opioid antagonist; wherein the stopper is only advanced a predetermined distance by a plunger assembly including a plunger rod, an actuator including at least one guide rail, and a spacer, wherein the at least one guide rail travels against a front surface of the spacer, wherein the plunger assembly is configured to move the stopper without a user touching the plunger rod. 14. The method of claim 13, wherein the syringe is housed in an encasement. 15. The method of claim 14, wherein the encasement includes a window configured to allow the user to view the at least one opioid antagonist in the syringe. 16. The method of claim 14, wherein the encasement includes a needle guard configured to allow the user to cover a needle after use. 17. The method of claim 13, wherein the at least one opioid antagonist is naloxone, a salt thereof, a derivative thereof, or a prodrug thereof. 18. The method of claim 17, wherein the at least one opioid antagonist is naloxone. 19. The method of claim 13, wherein the actuator and the spacer are configured to be secured around the plunger rod and provide the predetermined distance. 20. The method of claim 13, wherein the actuator and the spacer are configured to provide the predetermined distance between a start point and an end point. 21. The method of claim 13, wherein the advancing of the stopper the predetermined distance is configured to deliver about 5 mg of naloxone or a salt thereof. 22. The method of claim 13, wherein the advancing of the stopper the predetermined distance is configured to deliver about 100 mg of naloxone or a salt thereof.

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