Claims for Patent: 4,009,197
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Summary for Patent: 4,009,197
Title: | 2-(6-Substituted-2'-naphthyl) acetic acid derivatives and the salts and esters thereof |
Abstract: | 2-(6'-Substituted-2'-naphthyl)acetic acid derivatives substituted at the 2-position of the acetic acid moiety with methyl, methylene or halomethylene and the salts and esters thereof have anti-inflammatory, analgesic and anti-pyretic activities. |
Inventor(s): | Fried; John H. (Palo Alto, CA), Harrison; Ian T. (Palo Alto, CA) |
Assignee: | Syntex Corporation (Panama, PM) |
Application Number: | 05/573,483 |
Patent Claims: |
1. The isoamyl ester of d 2-(6'-methoxy-2'-naphthyl)propionic acid.
2. A compound selected from the group consisting of 2-(6'-methoxy-2'-naphthyl)propionic acid and the pharmaceutically acceptable salts thereof. 3. A compound selected from the group consisting of d 2-(6'-methoxy-2'-naphthyl)propionic acid and the pharmaceutically acceptable salts thereof. 4. A compound selected from the group consisting of 2-(6'-difluoromethoxy-2'-naphthyl)propionic acid and the pharmaceutically acceptable salts thereof. 5. A compound of claim 4 selected from the group consisting of dl-, d- and 1-2-(6'-difluoromethoxy-2'-naphthyl)propionic acid. 6. As a compound of claim 5, d 2-(6'-difluoromethoxy-2'-naphthyl)propionic acid. 7. The sodium salt of d 2-(6'-methoxy-2'-naphthyl)propionic acid. 8. The sodium salt of 2-(6'-methoxy-2'-naphthyl)propionic acid. 9. The pharmaceutically acceptable salts of 2-(6'-methoxy-2'-naphthyl)propionic acid. 10. The pharmaceutically acceptable salts of d 2-(6'-methoxy-2'-naphthyl)propionic acid. 11. 1 isoamyl 2-(6'-methoxy-2'-naphthyl)propionate. |
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