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Last Updated: April 2, 2025

Claims for Patent: 4,339,445

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Summary for Patent: 4,339,445

Title:	Method for combating virus infection
Abstract:	A method for the selective treatment of virus infections in animals and man and a method of treating cancer caused by viruses, comprising administering to a host so infected a therapeutically effective amount of phosphonoformic acid or a physiologically acceptable salt thereof.
Inventor(s):	Eriksson; Bertil F. H. (Sodertalje, SE), Helgstrand; Ake J. E. (Enhorna, SE), Misiorny; Alfons (Bandhagen, SE), Stening; Goran B. (Sodertalje, SE), Stridh; Stig-Ake A. (Sodertalje, SE)
Assignee:	Astra Lakemedel Aktiebolag (Sodertalje, SE)
Application Number:	05/971,931
Patent Claims:	1. A method for inhibiting the replication of hepatitis B virus in animals or man, by administering to an animal or man in need of such treatment phosphonoformic acid or a physiologically acceptable salt thereof in an amount sufficient for inhibiting said replication. 2. A method for the treatment of infections caused by hepatitis virus in animals or man by administering to an animal or man in need of such treatment phosphonoformic acid or a physiologically acceptable salt thereof in an amount effective to treat said infection. 3. A method according to claim 2, wherein said animal in need of treatment is treated with the trisodium salt of phosphonoformic acid. 4. A method for the treatment of infections caused by hepatitis B virus in animals man by administering to an animal or man in need of such treatment phosphonoformic acid or a physiologically acceptable salt thereof in an amount effective to treat said infection. 5. The method according to claim 4, wherein said animal in need of treatment is treated with the trisodium salt of phosphonoformic acid. 6. A method for inhibiting the replication of hepatitis virus in animals man by administering to an animal or man in need of such treatment phosphonoformic acid or a physiologically acceptable salt thereof in an amount sufficient for inhibiting replication. 7. The method according to claim 6, wherein said animal in need of treatment is treated with the trisodium salt of phosphonoformic acid.

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