Claims for Patent: 4,386,104

Summary for Patent: 4,386,104

Title:	Process for the treatment of acne
Abstract:	There is disclosed a composition for the treatment of acne, hyperpigmentary dermatoses or skin hyperpigmentation which contains dicarboxylic acids containing 7 to 13 carbon atoms or certain derivatives thereof that contain reducing functional group or a salt thereof. There are also disclosed methods for preparing mercapto derivatives of these dicarboxylic acids.
Inventor(s):	Nazzaro-Porro; Marcella (Rome, IT)
Assignee:
Application Number:	06/278,720
Patent Claims:	1. A method for the treatment of an individual exhibiting acne which comprises administering to said individual a therapeutically effective amount of an active ingredient in a pharmaceutically acceptable carrier until said condition is reduced or its further development is arrested wherein said active ingredient is at least one dicarboxylic acid containing from 7 to 13 carbon atoms selected from the group consisting of pimelic acid, suberic acid, sebacic acid, azelaic acid, 1,9-nonanedicarboxylic acid, 1.10-decanedicarboxylic acid, and 1,11-undecanedicarboxylic acid or a mono or dimercapto derivative of said acid or a salt thereof. 2. A method as defined in claim 1 wherein said acid is administered orally. 3. A method as defined in claim 1 wherein said acid is administered by injection. 4. A method as defined in claim 1 wherein said acid is administered topically. 5. A method as defined in claim 1 wherein said dicarboxylic acid acid is azelaic acid. 6. A method as defined in claim 1 wherein said dicarboxylic acid is 1,10-decanedicarboxylic acid.