Claims for Patent: 4,451,458
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Summary for Patent: 4,451,458
| Title: | Method for the treatment of post-operative thrombosis |
| Abstract: | The invention provides novel pharmaceutical compositions useful in the treatment of thrombosis in mammals, comprising a mixture of dihydroergotamine or a related ergot alkaloid and heparin. |
| Inventor(s): | Buhlmann; Hans (Nuremberg, DE), Welzel; Dieter (Nuremberg, DE) |
| Assignee: | Sandoz Ltd. (Basel, CH) |
| Application Number: | 06/379,272 |
| Patent Claims: |
1. A method for the prophylactic treatment of post-operative thrombosis in mammals, comprising parenterally administering dihydroergotamine in conjunction with heparin,
wherein the administration is effected with a unit dose comprising about 0.5 mg. of dihydroergotamine and about 2500-5000 I.U. of heparin and said doses are administered two to four times daily.
2. A pharmaceutical composition useful in the prophylactic treatment of post-operative thrombosis in mammals, comprising in unit dosage form about 0.5 mg. of dihydroergotamine and about 2500-5000 I.U. of heparin. 3. A pharmaceutical composition useful in the prophylactic treatment of post-operative thrombosis in mammals, comprising in unit dosage form about 0.5 mg. of dihydroergotamine and about 5000 I.U. of heparin. |
