Claims for Patent: 4,489,070

Summary for Patent: 4,489,070

Title:	Betamethasone dipropionate cream
Abstract:	Disclosed is an elegant formulation of betamethasone dipropionate useful as a topical anti-inflammatory product.
Inventor(s):	Sandweiss; Varda E. (Forest Hills, NY), Stupak; Elliot (West Caldwell, NJ), Shapiro; Paul H. (West Caldwell, NJ)
Assignee:	Schering Corporation (Madison, NJ)
Application Number:	06/550,434
Patent Claims:	1. A topical pharmaceutical composition for the treatment of inflammation consisting essentially of 0.02 to 0.10 percent betamethasone dipropionate; 0 to 0.6 percent titanium dioxide; 1.0 to 2.5 percent Carbomer 940; sufficient base to adjust the pH to between pH 4 to pH 5.5; and about 60 to 80 percent of propylene glycol and about 20 to 40 percent water. 2. A pharmaceutical composition according to claim 1 wherein Carbomer 940 is present in an amount of about 2% by weight. 3. A pharmaceutical composition according to claim 1 consisting essentially of 0.06 to 0.08 percent betamethasone dipropionate; about 1.0 to 2.5 percent Carbomer 940; sufficient base to adjust the pH to between pH 4 to pH 5.5; and about 65 to 75 percent of propylene glycol and about 25 to 35 percent water. 4. A pharmaceutical composition according to claim 1 wherein said base is sodium hydroxide.