Claims for Patent: 4,661,493

Summary for Patent: 4,661,493

Title:	Tioconazole and related compounds for control of Herpes simplex virus
Abstract:	Topical vaginal forms of tioconazole and related antimicrobic compounds, especially miconazole, econazole, clotrimazole, butaconazole and ketoconazole, are useful for the control (chemotherapeutic and chemoprophylactic) of Herpes virus infections.
Inventor(s):	Gibbs; David L. (New York, NY)
Assignee:	Pfizer Inc. (New York, NY)
Application Number:	06/837,658
Patent Claims:	1. A method for the treatment of herpetic infections in a human infected thereby which comprises topically applying to the site of said infection an anti-herpetic amount of drug selected from the group consisting of tioconazole, econazole, clotrimazole, ketoconazole, butaconazole or a pharmaceutically acceptable acid addition salt thereof. 2. A method according to claim 1 wherein the drug is applied in the form of a cream or ointment comprising from about 1% to about 10% of said drug. 3. A method according to claim 2 wherein the drug is administered intravaginally. 4. The method according to claim 3 wherein the drug is tioconazole. 5. The method according to claim 3 wherein the drug is econazole. 6. The method according to claim 3 wherein the drug is clotrimazole. 7. The method according to claim 3 wherein the drug is butaconazole.