Claims for Patent: 4,731,478
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Summary for Patent: 4,731,478
| Title: | Sulfamoyl-substituted phenethylamine derivatives, their preparation, and pharmaceutical compositions, containing them |
| Abstract: | A novel process is provided for the preparation of optical isomers of certain sulfamoyl-substituted phenethylamine derivatives which exhibit .alpha.-adrenergic blocking agents which can be used for various treatments such as for the treatment of congestive heart failure. |
| Inventor(s): | Niigata; Kunihiro (Saitama, JP), Fujikura; Takashi (Saitama, JP) |
| Assignee: | Yamanouchi Pharmaceutical Co., Ltd. (Tokyo, JP) |
| Application Number: | 06/803,204 |
| Patent Claims: |
1. Optically active 5-{2-[2-(2-ethoxyphenoxy)ethyl-amino]-2-methylethyl}-2-methoxybenzenesulfo namide.
2. The [-] isomer of 5-{2-[2-(2-ethoxyphenoxy)ethyl-amino]-2-methylethyl}-2-methoxybenzenesulfo namide. 3. A pharmaceutical composition comprising an .alpha.-adrenergic blocking effective amount of the optically active compound of claim 1, and a pharmaceutically acceptable carrier. 4. The pharmaceutical composition of claim 3, wherein the optically active compound is the [-] isomer of 5-{2-[2-(2-ethoxyphenoxy)ethylamino]-2-methylethyl}-2-methoxybenzenesulfon amide. |
