Claims for Patent: 5,155,268
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Summary for Patent: 5,155,268
Title: | Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides |
Abstract: | The present invention provides novel sulfonanilide and benzene-alkylaminium compounds which are the products of processes utilizing novel intermediates. Both the novel compounds and the novel intermediates are useful for the therapeutic or prophylactic treatment of arrhythmic activity. |
Inventor(s): | Hester, Jr.; Jackson B. (Galesburg, MI) |
Assignee: | The Upjohn Company (Kalamazoo, MI) |
Application Number: | 07/423,499 |
Patent Claims: |
1. The compound selected from the group consisting of: (a) N,N-diethyl-N-heptyl-.beta.-hydroxy-4-[(methylsulfonyl)amino]benzeneethana minium bromide;
(b) N,N-diethyl-N-heptyl-.delta.-hydroxy-4-[(methylsulfonyl)amino]benzenebutan aminium bromide; and, (c) N,N-diethyl-N-heptyl-.gamma.-hydroxy-4-[(methylsulfonyl)amino]benzenepropa naminium bromide. 2. A hydroxy-alkylene compound and pharmaceutically acceptable salts thereof which is (a) N-(4-(4-(ethylheptylamino)-1-hydroxybutyl)phenyl)methanesulfonamide; or (b) N-(4-(4-dibutylamino)-1-hydroxybutyl)phenyl)methanesulfonamide. |
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