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Last Updated: December 22, 2024

Claims for Patent: 5,314,697


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Summary for Patent: 5,314,697
Title: Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
Abstract:A film-coated extended release oral dosage composition containing the nasal decongestant pseudoephedrine sulfate in a unique polymer matrix core and a film-coating on such core containing the non-sedating antihistamine, loratadine, and use of the said composition for treating patients showing the signs and symptoms associated with upper respiratory diseases and nasal congestion are disclosed.
Inventor(s): Kwan; Henry K. (Summit, NJ), Liebowitz; Stephen M. (Neshanic Station, NJ)
Assignee: Schering Corporation (Kenilworth, NJ)
Application Number:07/965,470
Patent Claims: 1. A film-coated extended release oral dosage composition comprising:

a. a matrix core comprising:

and

b. a coating on said core comprising:

2. A method of treating patients showing the signs and symptoms associated with upper respiratory diseases which comprises administering to such a patient the oral dosage composition of claim 1.

3. The oral dosage composition of claim 1 wherein 240 mg. of pseudoephedrine sulfate is in the core and 10 mg. of loratadine is in the coating.

4. A film-coated extended release oral dosage composition comprising:

a. a matrix core comprising:

and

b. a coating on said core comprising:

5. A method of treating a patient showing the signs and/or symptoms associated with upper respiratory diseases which comprises administering to such a patient the oral dosage form of claim 4.

6. A film-coated extended release oral dosage composition comprising:

a. a matrix core comprising:

and

b. a coating upon said core comprising:

7. A method of treating a patient suffering from the signs and symptoms associated with upper respiratory disease and nasal congestion which comprises administering to such a patient the oral dosage composition of claim 6.

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