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Last Updated: November 21, 2024

Claims for Patent: 5,314,697

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Summary for Patent: 5,314,697

Title:	Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
Abstract:	A film-coated extended release oral dosage composition containing the nasal decongestant pseudoephedrine sulfate in a unique polymer matrix core and a film-coating on such core containing the non-sedating antihistamine, loratadine, and use of the said composition for treating patients showing the signs and symptoms associated with upper respiratory diseases and nasal congestion are disclosed.
Inventor(s):	Kwan; Henry K. (Summit, NJ), Liebowitz; Stephen M. (Neshanic Station, NJ)
Assignee:	Schering Corporation (Kenilworth, NJ)
Application Number:	07/965,470
Patent Claims:	1. A film-coated extended release oral dosage composition comprising: a. a matrix core comprising: and b. a coating on said core comprising: 2. A method of treating patients showing the signs and symptoms associated with upper respiratory diseases which comprises administering to such a patient the oral dosage composition of claim 1. 3. The oral dosage composition of claim 1 wherein 240 mg. of pseudoephedrine sulfate is in the core and 10 mg. of loratadine is in the coating. 4. A film-coated extended release oral dosage composition comprising: a. a matrix core comprising: and b. a coating on said core comprising: 5. A method of treating a patient showing the signs and/or symptoms associated with upper respiratory diseases which comprises administering to such a patient the oral dosage form of claim 4. 6. A film-coated extended release oral dosage composition comprising: a. a matrix core comprising: and b. a coating upon said core comprising: 7. A method of treating a patient suffering from the signs and symptoms associated with upper respiratory disease and nasal congestion which comprises administering to such a patient the oral dosage composition of claim 6.

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