Claims for Patent: 5,472,969

Summary for Patent: 5,472,969

Title:	Method of inhibiting glycolipid synthesis
Abstract:	A method is disclosed for inhibiting the biosynthesis of glycolipids in cells capable of producing glycolipids comprising subjecting said cells to a glycolipid inhibitory effective amount of an N-alkyl derivative of 1,5-dideoxy-1,5-imino-D-glucitol in which said alkyl contains from 2-8 carbon atoms.
Inventor(s):	Platt; Frances M. (Oxford, GB), Neises; Gabrielle R. (Chesterfield, MO), Dwek; Raymond A. (Oxford, GB), Butters; Terry D. (Oxford, GB)
Assignee:	Monsanto Company (St. Louis, MO)
Application Number:	08/321,718
Patent Claims:	1. The method of treating a patient affected with Gaucher's disease comprising administering to said patient a glycolipid inhibitory effective amount of an N-alkyl derivative of 1,5-dideoxy-1,5-imino-D-glucitol in which said alky contains from 2-8 carbon atoms. 2. The method of claim 1 in which the alkyl group containing form 4-6 carbon atoms. 3. The method of claim 2 in which the alkyl group is butyl. 4. The method of claim 2 in which the alkyl group is hexyl.