You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: November 7, 2024

Claims for Patent: 5,607,942


✉ Email this page to a colleague

« Back to Dashboard


Summary for Patent: 5,607,942
Title: 7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives
Abstract:7-(1-Pyrrolidinyl)-3-quinolone- and -naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives, of the formula ##STR1## in which X.sup.1 is halogen, X.sup.2 is hydrogen, halogen, amino or other radical, R.sup.1 is alkyl, cycloalkyl, optionally substituted phenyl or other radical, R.sup.2 is hydrogen, alkyl or a dioxolylmethyl radical, R.sup.3 is ##STR2## and A is N, CH, C-halogen, or the like, or forms a bridge with R.sup.1, and addition products thereof.
Inventor(s): Petersen; Uwe (Leverkusen, DE), Schenke; Thomas (Bergisch-Gladbach, DE), Krebs; Andreas (Odenthal-Holz, DE), Grohe; Klaus (Odenthal, DE), Schriewer; Michael (Odenthal, DE), Haller; Ingo (Wuppertal, DE), Metzger; Karl G. (Wuppertal, DE), Endermann; Rainer (Wuppertal, DE), Zeiler; Hans-Joachim (Velbert, DE)
Assignee: Bayer Aktiengesellschaft (Leverkusen, DE)
Application Number:08/406,448
Patent Claims: 1. The compound 1-cyclopropyl-7-([S,S]-2,8-diazabicyclo-[4.3.0]non-8-yl)-6-fluoro-1,4-dihy dro-8-methoxy-4-oxo-3-quinolinecarboxylic acid having the formula: ##STR382## or an alkali metal, alkaline earth metal, silver or guanidinium salt thereof or a pharmaceutically utilizable hydrate or acid addition salt thereof, said compound substantially free of other enantiomers and stereoisomers.

2. The compound (1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-1,4- dihydro-4-oxo-3-quinolonecarboxylic acid) of the formula ##STR383## or an addition product thereof with water, an acid or an alkali.

3. An antibacterial composition comprising an antibacterially effective amount of a compound or addition product thereof according to claim 1 and a diluent.

4. An antibacterial composition comprising an antibacterially effective amount of a compound or addition product thereof according to claim 2 and a diluent.

5. A method of combating bacteria in a patient in need thereof which comprises administering to such patient an antibacterially effective amount of a compound or addition product thereof according to claim 1.

6. A method of promoting the growth of an animal which comprises administering to said animal a growth promoting effective amount of a compound or addition product thereof according to claim 1.

7. A method of combating bacteria in a patient in need thereof which comprises administering to such patient an antibacterially effective amount of a compound or addition product thereof according to claim 2.

8. A method of promoting the growth of an animal which comprises administering to said animal a growth promoting effective amount of a compound or addition product thereof according to claim 2.

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.