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Last Updated: April 2, 2025

Claims for Patent: 6,025,391

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Summary for Patent: 6,025,391

Title:	Enteric-coated pharmaceutical compositions of mycophenolate
Abstract:	Disclosed are pharmaceutical compositions which have been modified to release pharmaceutically acceptable mycophenolate salts in the upper part of the intestinal tract and methods of treatment using the pharmaceutical compositions.
Inventor(s):	Haeberlin; Barbara (Riehen, CH), Mak; Ching-Pong (Therwil, CH), Meinzer; Armin (Buggingen, DE), Vonderscher; Jacky (Riedisheim, FR)
Assignee:	Novartis AG (Basel, CH)
Application Number:	09/077,398
Patent Claims:	1. A pharmaceutical composition comprising a mycophenolate salt, the composition being adapted to prevent release of the mycophenolate salt in the stomach and to release the mycophenolate salt in the upper part of the intestinal tract. 2. A pharmaceutical composition comprising an enteric coated pharmaceutically acceptable mycophenolate salt. 3. A method of immunosuppressing a subject which comprises administering a therapeutically effective amount of enteric coated pharmaceutically acceptable mycophenolate salt or a composition of claim 1 to a subject in need of such immunosuppression, optionally with the simultaneous or separate administration of another immunosuppressant. 4. A composition containing an enteric coated pharmaceutically acceptable mycophenolate salt or a composition of claim 1 and another immunosuppressant for simultaneous, sequential or separate administration. 5. A pharmaceutical composition according to claim 1 wherein the mycophenolate salt is a mono-sodium salt. 6. A pharmaceutical composition according to claim 2 wherein the mycophenolate salt is a mono-sodium salt. 7. A method according to claim 3 wherein the mycophenolate salt is a mono-sodium salt. 8. A method according to claim 3 wherein said another immunosuppressant is cyclosporin. 9. A pharmaceutical composition according to claim 4 wherein the mycophenolate salt is a mono-sodium salt. 10. A pharmaceutical composition according to claim 9 wherein said another immunosuppressant is cyclosporin. 11. A pharmaceutical composition according to claim 4 wherein said another immunosuppressant is cyclosporin.

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