Claims for Patent: 6,284,804

Summary for Patent: 6,284,804

Title:	Topical suspension formulations containing ciprofloxacin and dexamethasone
Abstract:	Suspension formulations containing dexamethasone and ciprofloxacin are disclosed. The formulations contain a nonionic polymer, a nonionic surfactant and an ionic tonicity agent, but are physically stable and easily re-suspended. The formulations are intended for topical application to the eye, ear or nose.
Inventor(s):	Singh; Onkar N. (Arlington, TX), Bhagat; Haresh G. (Fort Worth, TX)
Assignee:	Alcon Universal Ltd. (Hunenberg, CH)
Application Number:	09/636,563
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 6,284,804
Patent Claims:	1. A topically administrable suspension composition intended for application to the eye, ear or nose consisting essentially of a) 0.1% (wt.) dexamethasone alcohol; b) 0.35% (wt.) ciprofloxacin hydrochloride, monohydrate; c) NaCI in an amount sufficient to cause the composition to have an osmolality of about 250-350 mOsm; d) 0.2% (wt.) hydroxyethyl cellulose; e) 0.05% (wt.) tyloxapol; f) a buffer comprising sodium acetate and acetic acid; g) 0.01% (wt.) benzalkonium chloride; h) 0.01% (wt.) edetate disodium; i) 0.6% (wt.) boric acid; and wherein the composition has a pH of 4.5.+-.0.2.