Optically active 5H-pyrrolo[3, 4-B]pyrazine derivative, its preparation and pharmaceutical compositions containing it
Abstract:
Dextrorotatory isomer of 6-(5-chloro-2-pyridyl)-5[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-di hydro-5H-pyrrolo[3,4-b]pyrazine, its preparation and pharmaceutical compositions containing it which are usable as tranquillizers and hypnotics.
Inventor(s):
Cotrel; Claude (Paris, FR), Roussel; Gerard (Soisy sur Seine, FR)
Assignee:
Sepracor Inc. (Marlborough, MA)
Application Number:
09/124,651
Patent Claims:
1. A method for improving sleep quality or time comprising the step of administering an effective quantity of
6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-d ihydro-5H-pyrrolo[3,4-b]pyrazine, or a pharmaceutically acceptable salt thereof, in the form of its dextrorotatory isomer and essentially free of its levorotatory isomer, to a
human.
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