Claims for Patent: 7,026,337

Summary for Patent: 7,026,337

Title:	Antimycotic gel having high active compound release
Abstract:	A pharmaceutical preparation comprising a hydrophilic gel-forming agent, water and a compound of the formula I ##STR00001## is suitable for the treatment and prophylaxis of dermatomycoses.
Inventor(s):	Bohn; Manfred (Hofheim, DE), Kraemer; Karl Theodor (Langen, DE), Markus; Astrid (Liederbach, DE)
Assignee:	Aventis Pharma Deutschland GmbH (Frankfurt am Main, DE)
Application Number:	10/690,597
Patent Claims:	1. A method of treatment or prophylaxis of dermatomycoses comprising administering a composition in a pharmacologically effective amount to a patient in need thereof wherein the composition is a gel composition and comprises: at least one hydrophilic gel-forming agent; at least one spreading agent; and an active component consisting essentially of at least one compound chosen from a compound of formula (I) and physiologically tolerable salts thereof: ##STR00003## wherein R.sup.1, R.sup.2, and R.sup.3, which are identical or different, are a hydrogen atom or alkyl group having 1 to 4 carbon atoms, and R.sup.4 is a saturated hydrocarbon radical having 6 to 9 carbon atoms; and wherein the composition is substantially free of any additional active components. 2. The method of claim 1, wherein the active component consists essentially of 1-hydroxy-4-methyl-6-cyclohexyl-2(1H)pyridone, at least one physiologically tolerable salt thereof, or a mixture of the foregoing. 3. The method of claim 1, wherein the active component consists essentially of 1-hydroxy-4-methyl-6-(2,4,4,-trimethylpentyl)-2(1H)pyridone, at least one physiologically tolerable salt thereof, or a mixture of the foregoing. 4. A method of treatment or prophylaxis of fungus of the foot comprising administering a composition in a pharmacologically effective amount to a patient in need thereof wherein the composition is a gel composition and comprises: at least one hydrophilic gel-forming agent; at least one spreading agent; and an active component, wherein the active component consists essentially of 1-hydroxy-4-methyl-6-cyclohexyl-2(1H)pyridone; and wherein the composition is substantially free of any additional active components. 5. A method of treatment or prophylaxis of fungus of the foot comprising administering a composition in a pharmacologically effective amount to a patient in need thereof wherein the composition is a gel composition and comprises: at least one hydrophilic gel-forming agent; at least one spreading agent; and an active component, wherein the active component consists essentially of 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)pyridone; and wherein the composition is substantially free of any additional active components.