Claims for Patent: 7,544,799

Summary for Patent: 7,544,799

Title:	Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use
Abstract:	The invention relates to a new crystalline form of the methanesulfonic acid addition salt of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-- 2-ylamino)phenyl]-benzamide of formula 1, which may be used for example for tumour therapy. ##STR00001##
Inventor(s):	Zimmermann; Jurg (Basel, CH), Sutter; Bertrand (Hesingue, FR), Burger; Hans M (Allschwil, CH)
Assignee:	Novartis AG (Basel, CH)
Application Number:	11/515,997
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 7,544,799
Patent Claims:	1. A crystalline form of the monomethanesulfonic acid addition salt of a compound of formula I, ##STR00004## having non-needle-shaped crystals. 2. A crystalline form according to claim 1 of the methanesulfonic acid addition salt of a compound of formula I, which comprises at least 95% by weight crystals of the .beta.-modification. 3. A crystalline form according to claim 1 of the methanesulfonic acid addition salt of a compound of formula I, which shows on X-ray diffraction a peak at an angle of refraction 2theta of 20.degree., said peak having a relative line intensity of about 65% as compared to the most intense line in the diagram. 4. A pharmaceutical composition, comprising the crystal form according to claim 1 of the methanesulfonic acid addition salt of a compound of formula I and a pharmaceutically acceptable carrier.