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Last Updated: December 22, 2024

Claims for Patent: 7,629,345

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Summary for Patent: 7,629,345

Title:	Prostaglandin derivatives
Abstract:	Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
Inventor(s):	Ongini; Ennio (Milan, IT), Chiroli; Valerio (Milan, IT), Benedini; Francesca (Milan, IT), Del Soldato; Piero (Monza, IT)
Assignee:	Nicox S.A. (Sophia Antipolis, FR)
Application Number:	12/210,975
Patent Claims:	1. A pharmaceutical composition comprising a compound of the formula ##STR00048## or a pharmaceutically acceptable salt or stereoisomer thereof, and a pharmaceutically acceptable carrier. 2. A pharmaceutical composition according to claim 1 in a suitable form for topical administration. 3. A pharmaceutical composition according to claim 1, wherein said compound is administered as a solution, suspension or emulsion in an ophthalmically acceptable vehicle. 4. A method for treating glaucoma or ocular hypertension, said method comprising contacting an effective intraocular pressure reducing amount of a pharmaceutical composition according to claim 2 with the eye in order to reduce eye pressure and to maintain said pressure on a reduced level. 5. A method for treating glaucoma or ocular hypertension, said method comprising contacting an effective intraocular pressure reducing amount of a pharmaceutical composition according to claim 3 with the eye in order to reduce eye pressure and to maintain said pressure on a reduced level.

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