Claims for Patent: 7,834,059
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Summary for Patent: 7,834,059
| Title: | Topical nepafenac formulations |
| Abstract: | Topical suspension compositions of nepafenac are disclosed. The compositions are especially suitable for topical ophthalmic administration. |
| Inventor(s): | Wong; Warren (Fort Worth, TX) |
| Assignee: | Alcon, Inc. (Hunenberg, CH) |
| Application Number: | 11/292,484 |
| Patent Claims: |
1. A method of treating ophthalmic inflammatory disorders in a human patient comprising topically administering to the patient a composition consisting of a) 0.1% (w/v)
nepafenac; b) 0.5% (w/v) carbomer; c) 0.01% (w/v) tyloxapol; d) 0.4% (w/v) sodium chloride; e) 2.4% (w/v) mannitol; f) a pH-adjusting agent in an amount sufficient to cause the composition to have a pH of 7.3-7.7; g) 0.005% (w/v) benzalkonium
chloride; h) 0.01% edetate disodium; and i) purified water.
2. In a method of treating ophthalmic inflammatory disorders in a human patient comprising topically administering to the patient an aqueous suspension composition comprising nepafenac, the improvement wherein the composition consists of a) 0.1% (w/v) nepafenac; b) 0.5% (w/v) carbomer; c) 0.01% (w/v) tyloxapol; d) 0.4% (w/v) sodium chloride; e) 2.4% (w/v) mannitol; f) a pH-adjusting agent in an amount sufficient to cause the composition to have a pH of 7.3-7.7; g) 0.005% (w/v) benzalkonium chloride; h) 0.01% edetate disodium; and i) purified water. |
