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Last Updated: November 17, 2024

Claims for Patent: 7,977,488


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Summary for Patent: 7,977,488
Title:1-heterocyclylsulfonyl, 2-aminomethyl, 5-(hetero-) aryl substituted 1-H-pyrrole derivatives as acid secretion inhibitors
Abstract: The present invention provides a compound having a superior acid secretion inhibitory effect and showing an antiulcer activity and the like. The present invention provides a compound represented by the formula (I) wherein R.sup.1 is a nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle, the nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R.sup.2 is an optionally substituted C.sub.6-14 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R.sup.3 and R.sup.4 are each a hydrogen atom, or one of R.sup.3 and R.sup.4 is a hydrogen atom and the other is an optionally substituted lower alkyl group, an acyl group, a halogen atom, a cyano group or a nitro group, and R.sup.5 is an alkyl group or a salt thereof. ##STR00001##
Inventor(s): Kajino; Masahiro (Osaka, JP), Hasuoka; Atsushi (Osaka, JP), Nishida; Haruyuki (Osaka, JP)
Assignee: Takeda Pharmaceutical Company Limited (Osaka, JP)
Application Number:11/991,307
Patent Claims: 1. 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methy- lmethanamine or a salt thereof.

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