You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: December 22, 2024

Claims for Patent: 8,007,830

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 8,007,830

Title:	Granule formation
Abstract:	The present invention relates to oral granules of montelukast sodium.
Inventor(s):	Down; Brian (Pierrefonds, CA)
Assignee:	Merck Frosst Canada & Co. (Quebec, CA)
Application Number:	12/069,124
Patent Claims:	1. A flowable and dispersible pharmaceutical composition which comprises (i) granules comprising a pharmaceutically acceptable substrate which is spray-dried mannitol agglomerated with a pharmaceutically acceptable binder, and coated with montelukast sodium, and (ii) a pharmaceutically acceptable lubricant; wherein said binder is selected from hydroxypropyl cellulose, hydroxypropyl methylcellulose, methylcellulose, ethylcellulose and polyvinylpyrrolidone; and said granules are formed by coating said substrate with an aqueous solution consisting of montelukast sodium followed by drying. 2. A composition of claim 1 wherein said binder is hydroxypropyl cellulose. 3. A composition of claim 1 wherein said lubricant is magnesium stearate or talc. 4. A composition of claim 1 wherein said lubricant is magnesium stearate. 5. A flowable and dispersible pharmaceutical composition which comprises (i) granules comprising a pharmaceutically acceptable substrate which is spray-dried mannitol agglomerated with hydroxypropyl cellulose, said substrate being coated with montelukast sodium, and (ii) magnesium stearate, and said granules are formed by coating said substrate with an aqueous solution consisting of montelukast sodium followed by drying.

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.