Claims for Patent: 8,058,267

Summary for Patent: 8,058,267

Title:	Steroids as agonists for FXR
Abstract:	The invention relates to compounds of formula (I): ##STR00001## wherein R is ethyl and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. The compounds of formula (I) are useful as FXR agonists.
Inventor(s):	Pellicciari; Roberto (Perugia, IT)
Assignee:	Intercept Pharmaceuticals, Inc. (New York, NY)
Application Number:	12/547,147
Patent Claims:	1. A method for the treatment of cholestatic liver disease comprising administering to a mammal a therapeutically effective amount of a compound of formula I: ##STR00007## or a pharmaceutically acceptable salt or amino acid conjugates thereof, wherein R is ethyl. 2. The method according to claim 1, wherein the compound is the glycine conjugate of a compound of formula I. 3. The method according to claim 1, wherein the compound is the taurine conjugate of a compound of formula I. 4. The method according to claim 1, wherein the compound is the pharmaceutically acceptable salt of a compound of formula I. 5. The method according to claim 1, wherein the mammal is a human.