Claims for Patent: 8,212,033

Summary for Patent: 8,212,033

Title:	Use of substituted quinazoline compounds in treating angiogenesis-related diseases
Abstract:	Quinazoline derivatives of the following formula:
Inventor(s):	Su Wei-Guo, Zhang Weihan, Yan Xiaoqiang, Cui Yumin, Ren Yongxin, Duan Jifeng
Assignee:	Hutchison Medipharma Enterprises Limited
Application Number:	US12893872
Patent Claims:	2. The method of claim 1 , wherein each of Rand Ris optionally substituted alkoxy.3. The method of claim 1 , wherein Ris optionally substituted methyl.4. The method of claim 3 , wherein Ris methyl.5. The method of claim 1 , wherein Ris —C(O)NRR claim 1 , each of Rand R claim 1 , independently claim 1 , being H claim 1 , alkyl claim 1 , alkenyl claim 1 , alkynyl claim 1 , cycloalkyl claim 1 , heterocycloalkyl claim 1 , aryl claim 1 , or heteroaryl claim 1 , or Rand R claim 1 , together with the nitrogen atom to which they are attached claim 1 , represent a 3-8 membered ring containing 1-3 heteroatoms;{'sub': a', 'b, 'wherein each of alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl for Rand Ris optionally substituted with at least one substituent chosen from halo, hydroxy, amino, cyano, nitro, mercapto, alkoxycarbonyl, amido, carboxy, alkanesulfonyl, alkylcarbonyl, carbamido, carbamoyl, thioureido, thiocyanato, sulfonamido, alkyl, alkenyl, alkynyl, alkoxy, aryl, heteroaryl, cycloalkyl, and heterocycloalkyl.'}6. The method of claim 5 , wherein each of Rand R claim 5 , independently claim 5 , is H claim 5 , optionally substituted alkyl claim 5 , or optionally substituted cycloalkyl.7. The method of claim 6 , wherein Ris optionally substituted methyl.8. The method of claim 6 , wherein Ris H and Ris optionally substituted methyl.9. The method of claim 6 , wherein each of Rand Ris methoxy.