Claims for Patent: 8,334,279

Summary for Patent: 8,334,279

Title:	Non-hormonal steroid modulators of NF-κB for treatment of disease
Abstract:	The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy.
Inventor(s):	McCall John M., Hoffman Eric, Nagaraju Kanneboyina
Assignee:	Validus Genetics
Application Number:	US13327628
Patent Claims:	2. The method as recited in claim 1 , wherein said muscular dystrophy is selected from the group consisting of Duchenne muscular dystrophy claim 1 , Becker muscular dystrophy claim 1 , limb girdle muscular dystrophy claim 1 , congenital muscular dystrophy claim 1 , facioscapulohumeral muscular dystrophy claim 1 , myotonic muscular dystrophy claim 1 , oculopharyngeal muscular dystrophy claim 1 , distal muscular dystrophy claim 1 , and Emery-Dreifuss muscular dystrophy.3. The method as recited in claim 2 , wherein said muscular dystrophy is Duchenne muscular dystrophy.4. The method as recited in claim 2 , wherein said muscular dystrophy is Becker muscular dystrophy.5. The method as recited in claim 2 , wherein said muscular dystrophy is limb girdle muscular dystrophy.6. The method as recited in claim 2 , wherein said muscular dystrophy is congenital muscular dystrophy.7. The method as recited in claim 2 , wherein said muscular dystrophy is facioscapulohumeral muscular dystrophy.8. The method as recited in claim 2 , wherein said muscular dystrophy is myotonic muscular dystrophy.9. The method as recited in claim 2 , wherein said muscular dystrophy is oculopharyngeal muscular dystrophy.10. The method as recited in claim 2 , wherein said muscular dystrophy is distal muscular dystrophy.11. The method as recited in claim 2 , wherein said muscular dystrophy is Emery-Dreifuss muscular dystrophy.