Claims for Patent: 8,513,262

Summary for Patent: 8,513,262

Title:	Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors
Abstract:	A process for the preparation of a compound of formula (I) ##STR00001## comprising the steps: (a) reacting a compound of formula (II) ##STR00002## wherein L and L' are suitable leaving groups, with a compound of formula (III) UNH.sub.2 (III) to prepare a compound of formula (IV) ##STR00003## and subsequently (b) substituting the group R.sup.1 by replacement of the leaving group L'.
Inventor(s):	Carter; Malcolm Clive (Ware, GB), Cockerill; George Stuart (Bedford, GB), Lackey; Karen Elizabeth (Hillsborough, NC)
Assignee:	GlaxoSmithKline LLC (Philadelphia, PA)
Application Number:	12/691,784
Patent Claims:	1. A compound of the formula ##STR00057## or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical composition, comprising a compound of claim 1, together with one or more of pharmaceutically acceptable carriers, diluents or excipients. 3. A pharmaceutical composition as claimed in claim 2 in unit dosage form. 4. A compound of the formula ##STR00058## 5. A pharmaceutical composition, comprising the compound of claim 4, together with one or more of pharmaceutically acceptable carriers, diluents or excipients. 6. A pharmaceutical composition as claimed in claim 5 in unit dosage form. 7. A pharmaceutically acceptable salt of the compound of the formula ##STR00059## 8. A pharmaceutical composition, comprising the compound of claim 7, together with one or more of pharmaceutically acceptable carriers, diluents or excipients. 9. A pharmaceutical composition as claimed in claim 7 in unit dosage form.