You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: December 27, 2024

Claims for Patent: 8,546,367

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 8,546,367

Title:	Synthetic bile acid compositions and methods
Abstract:	Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
Inventor(s):	Moriarty; Robert M. (Michiana City, IN), David; Nathaniel E. (Los Angeles, CA), Mahmood; Nadir Ahmeduddin (Calabasas, CA)
Assignee:	Kythera Biopharmaceuticals, Inc. (Calabasas, CA)
Application Number:	13/486,945
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 8,546,367
Patent Claims:	1. A composition comprising deoxycholate and at least one pharmaceutically acceptable excipient and/or carrier, wherein the deoxycholate has a .sup.14C content of less than 1 ppt. 2. The composition of claim 1, wherein the deoxycholate has a .sup.14C content of less than 0.9 ppt. 3. An aqueous pharmaceutical composition comprising deoxycholate and at least one pharmaceutically acceptable excipient and/or carrier, wherein the deoxycholate has a .sup.14C content of less than 1 ppt. 4. The composition of claim 3, wherein the DCA has a .sup.14C content of less than 0.9 ppt. 5. An aqueous pharmaceutical composition comprising deoxycholate, phosphatidyl choline, and at least one pharmaceutically acceptable excipient and/or carrier, wherein the deoxycholate has a .sup.14C content of less than 1 ppt. 6. The composition of claim 5, wherein the DCA has a .sup.14C content of less than 0.9 ppt. 7. The composition of claim 1, wherein the deoxycholate has a .sup.14C content of 0.87 ppt. 8. The composition of claim 1, wherein the deoxycholate has a .sup.14C content of 0.88 ppt. 9. The composition of claim 1, wherein the deoxycholate has a .sup.14C content of 0.89 ppt. 10. The composition of claim 3, wherein the deoxycholate has a .sup.14C content of 0.87 ppt. 11. The composition of claim 3, wherein the deoxycholate has a .sup.14C content of 0.88 ppt. 12. The composition of claim 3, wherein the deoxycholate has a .sup.14C content of 0.89 ppt. 13. The composition of claim 5, wherein the deoxycholate has a .sup.14C content of 0.87 ppt. 14. The composition of claim 5, wherein the deoxycholate has a .sup.14C content of 0.88 ppt. 15. The composition of claim 5, wherein the deoxycholate has a .sup.14C content of 0.89 ppt. 16. A method for removing fat cells, said method comprising contacting said fat cells with an effective amount of a pharmaceutically acceptable salt of a deoxycholic acid (DCA), wherein said DCA has a .sup.14C content of less than 1 ppt.

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.