Claims for Patent: 8,642,600
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Summary for Patent: 8,642,600
| Title: | Method of treating autism |
| Abstract: | The present invention relates to a method of treating a patient suffering from a disorder of the central nervous system associated with 5-HT.sub.1A receptor subtype, comprising as an active ingredient a carbostyril derivative or a salt thereof represented by the formula (1): ##STR00001## wherein the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is a single or a double bond. |
| Inventor(s): | Jordan; Shaun (Germantown, MD), Kikuchi; Tetsuro (Tokushima, JP), Tottori; Katsura (Kamiita-cho, JP), Hirose; Tsuyoshi (Tokushima, JP), Uwahodo; Yasufumi (Tokushima, JP) |
| Assignee: | Otsuka Pharmaceutical Co., Ltd. (Tokyo, JP) |
| Application Number: | 13/185,879 |
| Patent Claims: |
1. A method of treating a patient suffering from autism, which comprises administering to said patient a therapeutically effective amount of a carbostyril compound of
formula (1), or a pharmaceutically acceptable salt or solvate thereof, wherein said patient is a mammal: ##STR00003## wherein the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is a single or a double bond.
2. The method of claim 1, wherein the carbostyril compound is 7-{4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy}-3,4-dihydrocarbostyril- . |
