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Last Updated: December 22, 2024

Claims for Patent: 8,697,748

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Summary for Patent: 8,697,748

Title:	Glycogen or polysaccharide storage disease treatment method
Abstract:	A method for treating glycogen storage disease by administering an effective amount of a composition that includes ketogenic odd carbon fatty acids that ameliorate the symptoms of these diseases.
Inventor(s):	Roe; Charles R. (Rockwall, TX)
Assignee:	Baylor Research Institute (Dallas, TX)
Application Number:	13/343,578
Patent Claims:	1. A composition comprising an active agent, wherein the active agent consists essentially of a triheptanoin, and wherein the composition has an acid value of 0.1 or less mg KOH/gr, a hydroxyl value of 2.8 or less mg KOH/gr. 2. The composition of claim 1, wherein the composition is provided in an amount suitable for administration in a range of 1 to 4 grams per kilogram body weight per day. 3. The composition of claim 1, wherein the composition is provided in an amount suitable for administration in a range of 1 to 3 grams per kilogram body weight per day. 4. The composition of claim 1, wherein the composition is provided in an amount suitable for administration in a range of 1 to 2 grams per kilogram body weight per day. 5. The composition of claim 1, wherein the composition is provided in an amount suitable for administration in a range of 0.1 to 2 grams per kilogram body weight per day. 6. The composition of claim 1, wherein the composition is in a dosage unit, wherein the dosage unit comprises at least 15 grams of the triheptanoin. 7. The composition of claim 6, wherein the dosage unit comprises 15 to 75 grams of the triheptanoin. 8. The composition of claim 6, wherein the dosage unit comprises 75 grams of the triheptanoin. 9. The composition of claim 1, wherein the composition is provided in an amount suitable for providing 15% to 40% of the daily dietary calories of a human. 10. The composition of claim 1, wherein the composition is provided in an amount suitable for providing 20% to 35% of the daily dietary calories of a human. 11. The composition of claim 1, wherein the composition is provided in an amount suitable for providing 25% to 35% of the daily dietary calories of a human. 12. The composition of claim 1, wherein the composition is provided in an amount suitable for providing 30% of the daily dietary calories of a human. 13. The composition of claim 1, wherein the composition is provided in an amount suitable for providing 25% of the daily dietary calories of a human. 14. The composition of claim 1, wherein the composition is a nutritional supplement. 15. The composition of claim 1, wherein the composition is a dietary formulation. 16. The composition of claim 1, wherein the composition is a pharmaceutical composition. 17. The composition of claim 1, wherein the composition is administered parenterally. 18. The composition of claim 1, wherein the composition is administered enterally. 19. The composition of claim 1, wherein the composition is administered orally. 20. The composition of claim 1, wherein the composition is provided in an amount suitable for administration in a range of about 1 gram per kilogram body weight per day for an adult for at least 7 or 14 days. 21. The composition of claim 1, wherein the composition is provided in an amount suitable for administration in a range of about 2 to 4 grams per kilogram body weight per day for at least 7 or 14 days. 22. The composition of claim 1, wherein the composition is provided in an amount suitable for administration in a range of about 1 to 2 grams per kilogram body weight per day for at least 7 or 14 days. 23. The composition of claim 1, wherein the dosage unit is at least 25% of the daily fatty acid dose for an adult. 24. The composition of claim 1, wherein the composition is provided in an amount suitable for administration in a range of about 1 to 4 grams per kilogram body weight per day for infants or 0.1 to 2 grams per kilogram body weight per day for adults. 25. The composition of claim 1, wherein the composition does not contain long-chain or very long-chain fatty acid.

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