Claims for Patent: 8,802,137
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Summary for Patent: 8,802,137
| Title: | Sustained release of antiinfectives |
| Abstract: | Provided are lipid antiinfective formulations substantially free of anionic lipids with a lipid to antiinfective ratio is about 1:1 to about 4:1, and a mean average diameter of less than about 1 .mu.m. Also provided is a method of preparing a lipid antiinfective formulation comprising an infusion process. Also provided are lipid antiinfective formulations wherein the lipid to drug ratio is about 1:1 or less, about 0.75:1 or less, or about 0.50:1 or less prepared by an in line fusion process. The present invention also relates to a method of treating a patient with a pulmonary infection comprising administering to the patient a therapeutically effective amount of a lipid antiinfective formulation of the present invention. The present invention also relates to a method of treating a patient for cystic fibrosis comprising administering to the patient a therapeutically effective amount of a lipid antiinfective formulation of the present invention. |
| Inventor(s): | Boni; Lawrence T. (Monmouth Junction, NJ), Miller; Brian S. (Mercerville, NJ), Malinin; Vladimir (Plainsboro, NJ), Li; Xingong (Robbinsville, NJ) |
| Assignee: | Insmed Incorporated (Monmouth Junction, NJ) |
| Application Number: | 12/748,756 |
| Patent Claims: |
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ISSN: 2162-2639
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