Claims for Patent: 9,127,276

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Summary for Patent: 9,127,276

Title:	Conjugated antisense compounds and their use
Abstract:	Provided herein are oligomeric compounds with conjugate groups. In certain embodiments, the oligomeric compounds are conjugated to N-Acetylgalactosamine.
Inventor(s):	Prakash Thazha P., Seth Punit P., Swayze Eric E.
Assignee:	Isis Pharmaceuticals, Inc.
Application Number:	US14267842
Patent Claims:	2. The compound of claim 1 , wherein the linker comprises an amine claim 1 , an amide claim 1 , an ester claim 1 , an ether claim 1 , a pyrrolidine claim 1 , PEG claim 1 , a polyamide claim 1 , or a disulfide bond.3. The compound of claim 1 , wherein the linker does not comprise a pyrrolidine.

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