Claims for Patent: 9,296,694

Summary for Patent: 9,296,694

Title:	Azacyclic compounds
Abstract:	Compounds and methods are provided for the treatment of disease conditions in which modification of serotonergic receptor activity has a beneficial effect. In the method, an effective amount of a compound is adminstered to a patient in need of such treatment.
Inventor(s):	Andersson; Carl-Magnus A. (Glostrup, DK), Croston; Glenn (San Diego, CA), Hansen; Eva Louise (Glostrup, DK), Uldam; Allan Kjaersgaard (Glostrup, DK)
Assignee:	ACADIA PHARMACEUTICALS INC. (San Diego, CA)
Application Number:	14/628,156
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 9,296,694
Patent Claims:	1. A compound of formula (I) ##STR00010## or a pharmaceutically acceptable salt thereof, wherein Z is ##STR00011## in which R is a hydrogen, a lower alkyl group, a cyclic organyl group, or a substituted or unsubstituted aralkyl or heteroaralkyl group; and n is 1; X.sub.1 is NH or N(lower alkyl) group; X.sub.2 is methylene; Y.sub.1 is methylene; Y.sub.2 is a bond, methylene, ethylene, or vinylene; Ar.sub.1 and Ar.sub.e are phenyl groups p-substituted with a substituent selected from the group consisting of lower alkyl, lower alkoxy and halogen; and W is oxygen. 2. The compound or pharmaceutically acceptable salt of claim 1, wherein R is a lower alkyl group. 3. The compound or pharmaceutically acceptable salt of claim 2, wherein R is selected from the group consisting of methyl, ethyl, propyl, butyl, methylbutyl, cyclopropyl, cyclohexyl, iso-propyl and tert-butyl. 4. The compound or pharmaceutically acceptable salt of claim 2, wherein aR.sub.1 and Ar.sub.2 are p-substituted with different substituents.