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Last Updated: July 17, 2024

Claims for Patent: 9,670,147


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Summary for Patent: 9,670,147
Title:Antioxidant inflammation modulators: oleanolic acid derivatives with amino and other modifications at C-17
Abstract:This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula:
Inventor(s):Anderson Eric, Jiang Xin, Visnick Melean
Assignee:REATA PHARMACEUTICALS, INC.
Application Number:US14753297
Patent Claims: 8. The compound of claim 1 , wherein Xis ORand Ris absent.9. The compound of claim 1 , wherein Xis hydrogen.10. The compound of claim 1 , wherein Y is NRR.11. The compound of claim 1 , wherein Ror Ris hydrogen.12. The compound of claim 1 , wherein Ror Rcomprises a fluoro group.13. The compound of claim 1 , wherein Ris acyl.14. The compound of claim 1 , wherein Ris substituted acyl.15. The compound of claim 1 , wherein R′ is hydrogen.16. The compound of claim 1 , wherein R′ is cyano.17. The compound of claim 1 , wherein Ris absent.18. The compound of claim 1 , wherein Rand Rare each methyl.19. The compound of claim 1 , wherein Rand Rare each hydrogen.20. The compound of claim 1 , wherein the bond joining carbon 1 and carbon 2 is a double bond.21. The compound of claim 1 , wherein the bond joining carbon 9 and carbon 11 is a double bond.22. The compound of claim 1 , wherein the bond joining carbon 12 and carbon 13 is a single bond.23. The compound of claim 1 , wherein the bond joining carbon 13 and carbon 18 is a single bond.

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