Claims for Patent: 9,962,376

Summary for Patent: 9,962,376

Title:	Methods and ophthalmic devices used in the treatment of ocular allergies
Abstract:	Ophthalmic devices and methods of treating allergic conjunctivitis are disclosed herein.
Inventor(s):	Raja; Ranganath R. (Jacksonville, FL), Mahadevan; Shivkumar (Orange Park, FL), Alti; Azaam (Jacksonville, FL), Molock; Frank F. (Orange Park, FL), Pall; Brain (Jacksonville, FL)
Assignee:	Johnson & Johnson Vision Care, Inc. (Jacksonville, FL)
Application Number:	11/686,979
Patent Claims:	1. An ophthalmic device comprising a sterile etafilcon A contact lens sealed in a contact lens package said contact lens comprising a minimum effective amount of about 10 .mu.g to about 25 .mu.g of an anti-allergic agent selected from the group consisting of ketotifen, its pharmaceutically acceptable salts and mixtures thereof, wherein, the ophthalmic device is formed by adding the anti-allergic agent to a contact lens solution, placing the contact lens in a contact lens package with said contact lens solution and anti-allergic agent, sealing the contact lens package containing the contact lens, contact lens solution and anti-allergic agent; and sterilizing the contact lens package, wherein said contact lens releases between about 10% and about 90% of its contained anti-allergic agent between administering the contact lens to the eye and about 60 minutes. 2. The ophthalmic device of claim 1 wherein the anti-allergic agent is ketotifen fumarate. 3. The ophthalmic device of claim 1 wherein the anti-allergic agent is ketotifen fumarate. 4. The ophthalmic device of claim 1 wherein said ophthalmic device, anti-allergic agent and contact lens solution are sterilized at conditions from about 100.degree. C. for about 8 hours to about 150.degree. C. for about 0.5 minutes. 5. The ophthalmic device of claim 1 wherein said ophthalmic device, anti-allergic agent and contact lens solution are sterilized at conditions from about 115.degree. C. for about 2.5 hours to about 130.degree. C. for about 5.0 minutes. 6. The ophthalmic device of claim 1 wherein said ophthalmic device, anti-allergic agent and contact lens solution are sterilized at about 124.degree. C. for about 18 minutes.