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Last Updated: July 27, 2024

Claims for Patent: 9,987,262


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Summary for Patent: 9,987,262
Title:Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
Abstract:Provided herein are solid forms comprising {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions comprising the solid forms, methods of making the solid forms and methods of their use for the treatment of various diseases and/or disorders.
Inventor(s):Copp James Densmore, Newman Ann W., Luong Anne
Assignee:Akebia Therapeutics, Inc.
Application Number:US15608186
Patent Claims: 3. The method of claim 1 , wherein the anemia is anemia secondary to or associated with chronic kidney disease.4. The method of claim 2 , wherein the anemia is anemia secondary to or associated with chronic kidney disease.5. The method of claim 1 , wherein the crystalline compound comprises less than 5% by weight of any other crystalline form of Compound (I).6. The method of claim 2 , wherein the pharmaceutical composition comprises less than 5% by weight of any other crystalline form of Compound (I).7. The method of claim 5 , wherein the anemia is anemia secondary to or associated with chronic kidney disease.8. The method of claim 6 , wherein the anemia is anemia secondary to or associated with chronic kidney disease.9. The method of claim 1 , wherein the crystalline Compound (I) is at least 99.5% pure as measured by HPLC.11. The method of claim 1 , wherein the therapeutically effective amount of the crystalline Compound (I) comprises less than 5% by weight of any amorphous form of Compound (I).12. The method of claim 2 , wherein the crystalline Compound (I) is at least 99.5% pure as measured by HPLC.14. The method of claim 2 , wherein the pharmaceutical composition comprises less than 5% by weight of amorphous form of Compound (I).

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