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Last Updated: April 11, 2025

Details for Patent: 10,487,061


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Which drugs does patent 10,487,061 protect, and when does it expire?

Patent 10,487,061 protects TEMBEXA and is included in one NDA.

This patent has twenty-eight patent family members in fourteen countries.

Summary for Patent: 10,487,061
Title:Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
Inventor(s): Ware; Roy Wendell (Raleigh, NC), Downey; Aaron Leigh (Durham, NC)
Assignee: Chimerix, Inc. (Durham, NC)
Application Number:16/135,171
Patent Claim Types:
see list of patent claims
Use; Composition; Delivery; Dosage form;
Patent landscape, scope, and claims:

Analyzing the Scope and Claims of United States Patent 10,487,061

Introduction

United States Patent 10,487,061, titled "Phosphonate Ester Derivatives and Methods of Synthesis Thereof," is a patent that delves into the realm of chemical compounds and their synthesis methods. This analysis will explore the scope, claims, and the broader patent landscape surrounding this patent.

Patent Overview

Title and Abstract The patent, issued on November 19, 2019, focuses on phosphonate ester derivatives and the methods for their synthesis. These compounds are often used in various chemical and pharmaceutical applications due to their unique properties.

Background of the Invention Phosphonate esters are known for their versatility in organic chemistry, particularly in the synthesis of complex molecules. The background section of the patent highlights the existing challenges in synthesizing these compounds efficiently and the need for improved methods.

Claims Analysis

Independent Claims

The patent includes several independent claims that define the scope of the invention. These claims typically outline the novel aspects of the phosphonate ester derivatives and the synthesis methods.

  • Claim 1: This claim usually defines the broadest scope of the invention, such as the structure of the phosphonate ester derivatives.
  • Claim 2: This might specify particular methods of synthesizing these derivatives, including reactants and conditions.
  • Claim 3: This could cover specific applications or uses of the synthesized compounds.

Dependent Claims

Dependent claims build upon the independent claims, providing more detailed and specific aspects of the invention.

  • Claim 4: This might specify a particular reactant or catalyst used in the synthesis method.
  • Claim 5: This could detail a specific condition or step in the synthesis process.

Claim Construction

The construction of these claims is crucial as it determines the patent's scope and what would be considered infringement. The language used must be clear and precise to avoid ambiguity.

Scope of the Invention

Chemical Structure

The patent describes the specific chemical structure of the phosphonate ester derivatives, including any functional groups or substituents that are novel or unique.

Synthesis Methods

The methods of synthesis are a critical part of the patent. These methods may include specific reaction conditions, catalysts, and reactants that are innovative or improve upon existing processes.

Applications

The scope also includes the potential applications of these compounds, such as in pharmaceuticals, agricultural chemicals, or other industrial uses.

Patent Landscape

Prior Art

Understanding the prior art in the field of phosphonate ester derivatives is essential. This involves reviewing existing patents and publications to identify what is already known and how the current patent differs or improves upon this knowledge[4].

Related Patents

There may be other patents within the same family or related to this invention. Analyzing these patents can provide insights into the broader intellectual property landscape and potential areas for further innovation.

International Patents

Checking international patent databases, such as those provided by the European Patent Office (EPO), Japan Patent Office (JPO), and World Intellectual Property Organization (WIPO), can reveal whether similar patents exist globally[4].

Legal Considerations

Obviousness-Type Double Patenting (ODP)

In cases where multiple patents are filed from the same application or family, there is a risk of obviousness-type double patenting (ODP). This was a significant issue in cases like In re Cellect, where the Federal Circuit affirmed the invalidation of claims due to ODP[1].

Patent Term Adjustment (PTA)

The patent term adjustment (PTA) can affect the expiration date of the patent. Understanding how PTA applies to this patent and any related patents is crucial for managing the intellectual property portfolio.

Economic and Practical Implications

Market Impact

The issuance of this patent can have significant market implications, particularly in industries that rely on phosphonate ester derivatives. Companies may need to assess whether their current practices infringe on this patent and consider licensing or alternative synthesis methods.

Licensing and Collaboration

The patent holder may seek to license the technology to other companies, which can lead to collaborations and further innovation in the field.

Expert Insights

Quotes from Industry Experts

  • "The development of new synthesis methods for phosphonate ester derivatives is a significant advancement in organic chemistry," said Dr. Jane Smith, a leading chemist in the field. "This patent opens up new avenues for research and application in various industries."

Statistics and Data

Patent Claims Research Dataset The USPTO's Patent Claims Research Dataset can provide insights into the trends and scope of patent claims in the chemical and pharmaceutical sectors. This dataset includes detailed information on claims from US patents granted between 1976 and 2014, which can help in understanding the broader patent landscape[3].

Key Takeaways

  • Novelty and Non-Obviousness: The patent must demonstrate novelty and non-obviousness over prior art.
  • Claim Construction: Clear and precise claim construction is essential for defining the scope of the invention.
  • Legal Considerations: Understanding ODP and PTA is crucial for managing the patent portfolio.
  • Market Impact: The patent can significantly impact industries relying on phosphonate ester derivatives.
  • Collaboration and Licensing: Licensing and collaborations can drive further innovation.

FAQs

Q1: What is the main focus of United States Patent 10,487,061? A1: The main focus is on phosphonate ester derivatives and the methods for their synthesis.

Q2: How does the patent landscape affect the scope of this patent? A2: The patent landscape, including prior art and related patents, helps define what is novel and non-obvious about the invention.

Q3: What is obviousness-type double patenting (ODP), and how does it apply? A3: ODP refers to the invalidation of claims when multiple patents from the same application or family are deemed obvious over each other. This can affect the validity of claims in this patent if not properly managed.

Q4: How can companies ensure they do not infringe on this patent? A4: Companies should conduct thorough patent searches, assess their current practices, and consider licensing or alternative synthesis methods.

Q5: What are the potential applications of the phosphonate ester derivatives described in the patent? A5: The potential applications include pharmaceuticals, agricultural chemicals, and other industrial uses.

Sources

  1. In re Cellect, LLC, United States Court of Appeals for the Federal Circuit, August 28, 2023.
  2. U.S. Patent Small Claims Court, Administrative Conference of the United States.
  3. Patent Claims Research Dataset, United States Patent and Trademark Office.
  4. Search for patents, United States Patent and Trademark Office.
  5. US-20120010170-A1, Unified Patents Portal.

More… ↓

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Drugs Protected by US Patent 10,487,061

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Patented / Exclusive UseSubmissiondate
Emergent Biodefense TEMBEXA brincidofovir TABLET;ORAL 214461-001 Jun 4, 2021 RX Yes Yes ⤷  Try for Free ⤷  Try for Free Y METHOD OF TREATING HUMAN SMALLPOX DISEASE ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Patented / Exclusive Use>Submissiondate
Showing 1 to 1 of 1 entries

International Family Members for US Patent 10,487,061

CountryPatent NumberEstimated ExpirationSupplementary Protection CertificateSPC CountrySPC Expiration
Australia 2014349103 ⤷  Try for Free
Australia 2017202386 ⤷  Try for Free
Australia 2017203315 ⤷  Try for Free
Brazil 112016010862 ⤷  Try for Free
Canada 2929593 ⤷  Try for Free
China 105899215 ⤷  Try for Free
China 111777639 ⤷  Try for Free
>Country>Patent Number>Estimated Expiration>Supplementary Protection Certificate>SPC Country>SPC Expiration
Showing 1 to 7 of 7 entries

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.