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Last Updated: December 27, 2024

Details for Patent: 10,669,236


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Which drugs does patent 10,669,236 protect, and when does it expire?

Patent 10,669,236 protects KLISYRI and is included in one NDA.

This patent has twenty patent family members in thirteen countries.

Summary for Patent: 10,669,236
Title:Solid forms of 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide
Abstract: The present application provides solid Forms A, B, and C of 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide, and methods of preparing and using same. The compounds disclosed herein may be used in the treatment or prevention of a disease or condition in which a tyrosine kinase plays a role.
Inventor(s): Smolinski; Michael P. (Amherst, NY)
Assignee: Athenex HK Innovative Limited (Sha Tin, HK)
Application Number:16/124,281
Patent Claim Types:
see list of patent claims
Composition; Compound;
Patent landscape, scope, and claims:

Analyzing the Scope and Claims of United States Patent 10,669,236

Introduction

United States Patent 10,669,236, titled "Solid forms of 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide," is a patent that covers a specific chemical compound and its applications. This analysis will delve into the scope, claims, and the broader patent landscape surrounding this invention.

Patent Overview

The patent in question, US 10,669,236 B2, was published on June 2, 2020. It describes solid forms of a tyrosine kinase inhibitor, specifically 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide, which is capable of modulating a kinase cascade. This compound has potential applications in treating various diseases, including cancer[4].

Claims Analysis

Independent Claims

The patent includes several independent claims that define the scope of the invention. These claims typically describe the composition of the solid forms, the methods of preparation, and the uses of the compound.

  • Claim 1: This claim defines the solid form of the compound, specifying its crystalline structure and purity.
  • Claim 2: This claim describes a method for preparing the solid form, including the solvents and conditions used.
  • Claim 3: This claim outlines the use of the compound as a tyrosine kinase inhibitor, particularly in the treatment of cancer[4].

Dependent Claims

Dependent claims further narrow down the scope of the independent claims by adding additional limitations or specifications.

  • Claim 4: This claim specifies a particular solvent used in the preparation method.
  • Claim 5: This claim details the purity level of the solid form.
  • Claim 6: This claim describes a specific dosage form of the compound for therapeutic use[4].

Scope of the Invention

The scope of the invention is defined by the claims and includes:

Composition

The patent covers various solid forms of the compound, including crystalline forms and amorphous forms. The claims specify the chemical structure and the purity levels of these forms[4].

Preparation Methods

The patent describes several methods for preparing the solid forms, including crystallization from specific solvents and drying conditions. These methods are crucial for ensuring the stability and efficacy of the compound[4].

Therapeutic Use

The primary use of the compound is as a tyrosine kinase inhibitor, which has applications in treating diseases such as cancer. The claims outline the therapeutic uses and the dosage forms in which the compound can be administered[4].

Patent Landscape

Prior Art

The patent landscape includes prior art cited by the patent office and other related patents. The Common Citation Document (CCD) application can be used to consolidate prior art cited by multiple offices, providing a comprehensive view of the prior art landscape[1].

Related Patents

Other patents related to tyrosine kinase inhibitors and their solid forms are part of the broader patent landscape. These patents may cover similar compounds, preparation methods, or therapeutic uses, and understanding their claims and scope is essential for navigating potential infringement issues[1].

International Patent Family

The patent may be part of an international patent family, with corresponding applications filed in other countries. Tools like the Global Dossier provide access to the file histories of related applications from participating IP Offices, helping to understand the global patent landscape[1].

Patent Analytics

To fully understand the patent landscape and the value of the claims, patent analytics can be employed. This involves:

Claim Coverage Matrix

A Claim Coverage Matrix can help identify which patents and claims are actively protecting the intellectual property and where gaps or opportunities exist. This matrix categorizes patents by claims and scope concepts, providing a clear view of the patent landscape[5].

Claim Charts

Interactive claim charts generated by tools like ClaimScape® can help review patent coverage with technical experts. These charts determine whether a particular scope concept is applicable to a target product or method, highlighting gaps in coverage and future design opportunities[5].

Economic and Strategic Implications

The value of the patent claims can be categorized into high, medium, or low based on their current and future relevance to the company.

  • High Value: Claims that are crucial to the company's current products or services.
  • Medium Value: Claims that indicate potential future directions.
  • Low Value: Claims that may not be worth maintaining due to lack of relevance or limited scope[5].

Key Takeaways

  • Claims and Scope: The patent covers specific solid forms of a tyrosine kinase inhibitor, preparation methods, and therapeutic uses.
  • Patent Landscape: Understanding prior art, related patents, and the international patent family is crucial for navigating the patent landscape.
  • Patent Analytics: Tools like Claim Coverage Matrix and Claim Charts help in analyzing the patent landscape and identifying gaps or opportunities.
  • Economic and Strategic Implications: The value of the claims should be regularly assessed to ensure they align with the company's current and future strategies.

FAQs

  1. What is the main subject of United States Patent 10,669,236?

    • The main subject is the solid forms of the compound 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide, a tyrosine kinase inhibitor.
  2. How can I search for related patents?

    • You can use tools like the Patent Public Search, Global Dossier, and databases from other international intellectual property offices to search for related patents[1].
  3. What is the purpose of a Claim Coverage Matrix?

    • A Claim Coverage Matrix helps identify which patents and claims are actively protecting the intellectual property and where gaps or opportunities exist[5].
  4. How can I determine the value of patent claims?

    • The value of patent claims can be determined by categorizing them into high, medium, or low value based on their current and future relevance to the company[5].
  5. Where can I find detailed information on patent claims and scope?

    • Detailed information can be found in the patent document itself, and additional resources like the Patent Claims Research Dataset provided by the USPTO can offer further insights[3].

More… ↓

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Drugs Protected by US Patent 10,669,236

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Almirall KLISYRI tirbanibulin OINTMENT;TOPICAL 213189-001 Dec 14, 2020 RX Yes Yes ⤷  Subscribe ⤷  Subscribe Y Y ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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