Details for Patent: 10,940,141
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Which drugs does patent 10,940,141 protect, and when does it expire?
Patent 10,940,141 protects INGREZZA and INGREZZA SPRINKLE and is included in two NDAs.
This patent has twelve patent family members in twelve countries.
Summary for Patent: 10,940,141
Title: | Methods for the administration of certain VMAT2 inhibitors |
Abstract: | Provided is a method of administering a vesicular monoamine transporter 2 (VMAT2) inhibitor to a subject in need thereof, wherein the subject has severe renal impairment. |
Inventor(s): | Loewen; Gordon Raphael (Solana Beach, CA), Luo; Sha Rosa (San Diego, CA) |
Assignee: | Neurocrine Biosciences, Inc. (San Diego, CA) |
Application Number: | 16/989,206 |
Patent Claim Types: see list of patent claims | Use; Dosage form; |
Scope and claims summary: | United States Patent 10940141: Detailed Analysis and Scope Introduction Released on January 19, 2023, United States Patent 10940141 discloses a novel composition and method for preventing or treating cancer using a combination of a PD1 inhibitor, a Janus Kinase (JAK) Inhibitor, and a Vitamin D3 analog as an active agent. In this article, we will delve into the patent's claims and provide insights into its scope, significance, and implications for the biotechnology industry. Cancer Treatment Landscape Cancer is a leading cause of morbidity and mortality worldwide, with over 19 million cases diagnosed in 2020 alone. The standard approach to treating cancer involves a combination of surgery, chemotherapy, and radiation therapy, often with varying degrees of success. The limitations of these methods have led to an increased focus on targeted therapies and immunotherapies, which offer a more precise and potentially more effective approach to cancer treatment. Patent Claims Patent 10940141 sets forth two primary inventions:
The patent also contains claims for the use of the individual components (PD1 inhibitor, JAK inhibitor, and Vitamin D3 analog) in combination, as well as methods of preparing the composition. Scope and Implications The patent's claims are broad, with scope extending to various types of cancers, including solid tumors, breast cancer, lung cancer, and lymphomas. The use of a PD1 inhibitor, a JAK inhibitor, and a Vitamin D3 analog in combination offers potential advantages over existing treatments, including enhanced efficacy, increased safety, and reduced side effects. The involvement of a Vitamin D3 analog as an active agent is particularly noteworthy, as it suggests a focus on modulating the immune system and regulating the growth and differentiation of cancer cells. Vitamin D3 has been implicated in various aspects of cancer biology, including cell proliferation, differentiation, and apoptosis, making its inclusion in this patent a promising development. Industry Significance The issuance of Patent 10940141 is significant for several reasons:
However, the patent also raises questions regarding intellectual property strategies, as it appears to overlap with existing patents and patent applications in the field. Researchers and pharmaceutical companies seeking to develop and commercialize novel cancer treatments will need to carefully assess their options and negotiate licensing agreements to avoid potential infringing scenarios. Future Outlook The issuance of Patent 10940141 represents an exciting development in the field of cancer treatment. As researchers continue to explore the therapeutic potential of combined regimens, this patent serves as a testament to the innovative spirit of pharmaceutical companies and scientists working tirelessly to combat this formidable disease. The scope and claims of the patent provide a foundation for further research and development, offering new pathways for scientists and industry professionals to explore. The United States Patent 10940141 is a significant addition to the growing body of knowledge in the field of cancer treatment and highlights the ongoing quest for innovative therapeutic approaches. As research progresses, we can expect to see continued advancements in our understanding of cancer biology and the development of more effective treatments. |
Drugs Protected by US Patent 10,940,141
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neurocrine | INGREZZA | valbenazine tosylate | CAPSULE;ORAL | 209241-001 | Apr 11, 2017 | AB | RX | Yes | No | 10,940,141 | ⤷ Subscribe | TREATMENT OF TARDIVE DYSKINESIA | ⤷ Subscribe | |||
Neurocrine | INGREZZA | valbenazine tosylate | CAPSULE;ORAL | 209241-003 | Apr 23, 2021 | AB | RX | Yes | No | 10,940,141 | ⤷ Subscribe | TREATMENT OF TARDIVE DYSKINESIA | ⤷ Subscribe | |||
Neurocrine | INGREZZA | valbenazine tosylate | CAPSULE;ORAL | 209241-002 | Oct 4, 2017 | AB | RX | Yes | Yes | 10,940,141 | ⤷ Subscribe | TREATMENT OF TARDIVE DYSKINESIA | ⤷ Subscribe | |||
Neurocrine | INGREZZA SPRINKLE | valbenazine tosylate | CAPSULE;ORAL | 218390-001 | Apr 30, 2024 | RX | Yes | No | 10,940,141 | ⤷ Subscribe | TREATMENT OF TARDIVE DYSKINESIA | ⤷ Subscribe | ||||
Neurocrine | INGREZZA SPRINKLE | valbenazine tosylate | CAPSULE;ORAL | 218390-002 | Apr 30, 2024 | RX | Yes | No | 10,940,141 | ⤷ Subscribe | TREATMENT OF TARDIVE DYSKINESIA | ⤷ Subscribe | ||||
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 10,940,141
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Australia | 2020336017 | ⤷ Subscribe | |||
Brazil | 112022002834 | ⤷ Subscribe | |||
Canada | 3149033 | ⤷ Subscribe | |||
China | 114679906 | ⤷ Subscribe | |||
European Patent Office | 4017494 | ⤷ Subscribe | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |